Evidence map›Paper›PMID 32179923›Full record

ArticleSingapore medical journal2021

Help-seeking patterns and funding strategies in patients with pulmonary arterial hypertension on phosphodiesterase-5 inhibitors: an orphan disease with effective but costly treatment.

Yinghao Lim, Siti Munawarah Bte Maaroof, Ting Ting Low, Ivandito Kuntjoro, James Wl Yip, Edgar Tay

Abstract read
In one paragraph

Article in Singapore medical journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yinghao LimDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Siti Munawarah Bte MaaroofDepartment of Medical Social Work, National University Hospital, Singapore.
Ting Ting LowDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Ivandito KuntjoroDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
James Wl YipDepartment of Cardiology, National University Heart Centre Singapore, Singapore.
Edgar TayDepartment of Cardiology, National University Heart Centre Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPulmonary arterial hypertension (PAH) is associated with high medical and pharmaceutical costs. Phosphodiesterase type 5 (PDE5) inhibitors have been found to be beneficial but costly. They are not subsidised in Singapore except via the Medication Assistance Fund (MAF) Plus scheme. In this study, we described the help-seeking behaviour of patients and funding strategies for Singaporean patients on PDE5 inhibitors in our registry.

methodsWe consecutively recruited all patients with PAH who presented to our pulmonary hypertension specialty centre between 1 January 2003 and 29 December 2016. Singaporean patients on PDE5 inhibitors were included. Data recorded and analysed for this study included baseline demographics, whether the patients received MAF Plus funding, percentage of funding, and any additional source of subsidies.

results114 (77.0%) of 148 patients in the registry were Singapore citizens on PDE5 inhibitors. 75 (65.8%) of these 114 patients had been seen by a medical social worker, of whom 16 were on MAF Plus funding. 14 of the remaining 59 patients were subsidised by MediFund, whereas the remainder were self-paying. 30 (26.3%) patients in total were on some form of subsidy, and 28 (24.6%) patients were on combination therapy. Of this group, nine were receiving MAF Plus subsidies.

conclusionFewer than expected patients were found to be receiving drug subsidies for PAH. This was partly due to insufficient referrals and lack of requests for financial assistance. Patients on combination therapy had greater financial challenges. This study should spur us on to study funding gaps further and address them.

Indexed as

Help-Seeking BehaviorPulmonary Arterial HypertensionCyclic Nucleotide Phosphodiesterases, Type 5HumansPhosphodiesterase 5 InhibitorsRare DiseasesCyclic Nucleotide Phosphodiesterases, Type 5Phosphodiesterase 5 InhibitorsAsiahealthcare financingphosphodiesterase 5 inhibitorspulmonary hypertension

Identifiers

PMID32179923
PMCPMC8801821

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.