ArticleScientific reports2020
Congruency and reactivation aid memory integration through reinstatement of prior knowledge.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- A sleep schedule incorporating naps benefits the transformation of hierarchical knowledge.Sleep · 2022Trial
- The hippocampus rapidly integrates sequence representations during novel multistep predictions.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Article
- Binding items to contexts through conjunctive neural representations with the method of loci.Nature communications · 2026Article
- Affective schemas: Acquisition, updating, and inference.Emotion (Washington, D.C.) · 2026Article
- Related memories exhibit interference during learning in adults but later retrieval in children.PloS one · 2026Article
- Prefrontal Cortex Responses to Conflicting Information.Human brain mapping · 2025Article
- Rich autobiographical memory benefits from both novelty and similarity to other daily experiences.Scientific reports · 2025Article
- Targeting memory of embedded positive verbal content indirectly modulates negative visual memory.iScience · 2025Article
- How the New Interacts With the Old? Hippocampal Processing During Memory Encoding of Creative Associations With Remote or Close Inherent Semantic Relatedness.Human brain mapping · 2025Article
- The Hippocampus Rapidly Integrates Sequence Representations During Novel Multistep Predictions.bioRxiv : the preprint server for biology · 2025Article
- Rich autobiographical memory recall benefits from both novelty and similarity to other daily experiences.Research square · 2025Article
- Cortico-hippocampal interactions underlie schema-supported memory encoding in older adults.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Memory updating and the structure of event representations.Trends in cognitive sciences · 2025Review
- Neural codes track prior events in a narrative and predict subsequent memory for details.Communications psychology · 2025Article
- The effects of episodic context on memory integration.Scientific reports · 2024Article
- Context reexposure to bolster contextual dependency of emotional episodic memory.Scientific reports · 2023Article
- Predictions transform memories: How expected versus unexpected events are integrated or separated in memory.Neuroscience and biobehavioral reviews · 2023Review
- Conceptual relatedness promotes memory generalization at the cost of detailed recollection.Scientific reports · 2023Article
- The Assimilation of Novel Information into Schemata and Its Efficient Consolidation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Learning new words: Memory reactivation as a mechanism for strengthening and updating a novel word's meaning.Memory & cognition · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Building knowledge schemas that organize information and guide future learning is of great importance in everyday life. Such knowledge building is suggested to occur through reinstatement of prior knowledge during new learning, yielding integration of new with old memories supported by the medial prefrontal cortex (mPFC) and medial temporal lobe (MTL). Congruency with prior knowledge is also known to enhance subsequent memory. Yet, how reactivation and congruency interact to optimize memory integration is unknown. To investigate this question, we used an adapted AB-AC inference paradigm in combination with functional Magnetic Resonance Imaging (fMRI). Participants first studied an AB-association followed by an AC-association, so B (a scene) and C (an object) were indirectly linked through A (a pseudoword). BC-associations were either congruent or incongruent with prior knowledge (e.g. bathduck or hammer in a bathroom), and participants reported subjective B-reactivation strength while learning AC. Behaviorally, both congruency and reactivation enhanced memory integration. In the brain, these behavioral effects related to univariate and multivariate parametric effects in the MTL, mPFC, and Parahippocampal Place Area (PPA). Moreover, mPFC exhibited larger PPA-connectivity for more congruent associations. These outcomes provide insights into the neural mechanisms underlying memory enhancement, which has value for educational learning.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.