ArticleScientific reports2020
Prevalence and new onset of depression and anxiety among participants with AMD in a European cohort.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 24 citations in OpenAlex.
- Depression and associated factors among patients with common eye diseases at the University of Gondar Comprehensive and Specialized Hospital Northwest Ethiopia.Discover mental health · 2025Article
- Evaluating the Impact of Age-Related Macular Degeneration on Seasonal Affective Disorder: A Retrospective Cohort Study in a Chinese Population.Actas espanolas de psiquiatria · 2025Article
- Self-perceived and measured visual function, the impact of eye-disease, wellbeing, social determinants, and personality traits in Swedish 70-year-olds-results from the Gothenburg H70 Study.Acta ophthalmologica · 2025Article
- Causal Relationships Between Retinal Diseases and Psychiatric Disorders Have Implications for Precision Psychiatry.Molecular neurobiology · 2025Article
- Association of Age-Related Eye Diseases with Comorbidity of Coronary Heart Disease and Depression in a Population-Based Cohort Study.Psychology research and behavior management · 2025Article
- Daily Functionality of People with Low Vision: The Impact of Visual Acuity, Depression, and Life Orientation-A Cross-Sectional Study.Behavioural neurology · 2024Article
- Much higher prevalence of keratoconus than announced results of the Gutenberg Health Study (GHS).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2023Article
- Prevalence and risk factors for depression and anxiety in patients with nasolacrimal duct obstruction.Frontiers in psychiatry · 2023Article
- Mental health and visual acuity in patients with age-related macular degeneration.BMC ophthalmology · 2022Article
- Study on the Changes in Circadian Rhythm Before and After Treatment and the Influencing Factors in Patients with Depression.Neuropsychiatric disease and treatment · 2022Article
- Risk of anxiety and depression in patients with uveitis: a Meta-analysis.International journal of ophthalmology · 2022Article
- Seeing Beyond Anatomy: Quality of Life with Geographic Atrophy.Ophthalmology and therapy · 2021Article
- The prevalence of anxiety symptoms and disorders among ophthalmic disease patients.Therapeutic advances in ophthalmologyArticle
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Authors and funding
14 authors at 3 institutions in 3 countries.
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No grant is acknowledged in the PubMed record.
Abstract
To investigate the prevalence and new onset of depression and anxiety among subjects with age-related macular degeneration (AMD) and its association with AMD in a large European cohort with relatively good visual acuity. 11,834 participants enrolled in the German population-based Gutenberg Health Study were studied. AMD was diagnosed by grading of fundus photographs. Depression and anxiety were assessed with the Patient Health Questionnaire and the Generalized Anxiety Disorder-2 Scale, respectively. Logistic regression analyses were performed and adjusted for several parameters. 1,089 (9.2%) participants were diagnosed having AMD. Prevalence of depression in AMD and non-AMD participants was 7.2% and 8.0%, respectively and prevalence of anxiety was 4.2% and 7.0%, respectively. New onset of depression and anxiety at 5-year follow-up in AMD subjects was 2.6% and 3.6%, respectively. AMD was not associated with depression (OR 0.93; CI 95% 0.70-1.20; p = 0.62). AMD was associated with less anxiety (OR 0.67; CI 95% 0.47-0.93; p = 0.02). This is the first study analyzing both prevalence and new onset of depression and anxiety in AMD subjects. AMD- and non-AMD participants had a similar prevalence and new onset of depression in our population-based sample. Participants without AMD had a higher prevalence of anxiety. AMD was not associated with depression.
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