ArticleProceedings of the National Academy of Sciences of the United States of America2020
Honey bees harbor a diverse gut virome engaging in nested strain-level interactions with the microbiota.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Global research trends in bacteriophage and gut microbiota: a bibliometric and visual analysis from 2012 to 2025.Frontiers in microbiology · 2025Pooled it
- Host Range Breadth Correlates with Genic Diversity in Honeybee Phages.Genome biology and evolution · 2026Article
- The honey bee triad: a comprehensive catalogue of phages in the Apis mellifera gut microbiome.Nature communications · 2026Article
- Review
- Gut Phage Biobank: a collection of bacteriophages targeting human commensal bacteria.Nature communications · 2025Article
- Article
- Phage diversity mirrors bacterial strain diversity in the honey bee gut microbiota.Nature communications · 2025Article
- Antibiotic treatment of honey bee colonies alters early gut microbiome assembly and induces persistent dysbiosis in newly emerged workers.Scientific reports · 2025Article
- Evolutionary trends inmSystems · 2025Article
- Honey Bee Viromes From Varroa destructor-Resistant and Susceptible Colonies.Environmental microbiology reports · 2025Article
- Article
- Article
- A roadmap of isolating and investigating bacteriophage infecting human gut anaerobes.Essays in biochemistry · 2024Review
- Host specificity and cophylogeny in the "animal-gut bacteria-phage" tripartite system.NPJ biofilms and microbiomes · 2024Article
- Targeted viromes and total metagenomes capture distinct components of bee gut phage communities.Microbiome · 2024Article
- Apis mellifera filamentous virus from a honey bee gut microbiome survey in Hungary.Scientific reports · 2024Article
- The honeybee microbiota and its impact on health and disease.Nature reviews. Microbiology · 2024Review
- Metagenomic analysis of the honey bee queen microbiome reveals low bacterial diversity and Caudoviricetes phages.mSystems · 2024Article
- Chronic bee paralysis virus exploits host antimicrobial peptides and alters gut microbiota composition to facilitate viral infection.The ISME journal · 2024Article
- Tailed bacteriophages (Caudoviricetes) dominate the microbiome of a diseased stingless bee.Genetics and molecular biology · 2024Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The honey bee gut microbiota influences bee health and has become an important model to study the ecology and evolution of microbiota-host interactions. Yet, little is known about the phage community associated with the bee gut, despite its potential to modulate bacterial diversity or to govern important symbiotic functions. Here we analyzed two metagenomes derived from virus-like particles, analyzed the prevalence of the identified phages across 73 bacterial metagenomes from individual bees, and tested the host range of isolated phages. Our results show that the honey bee gut virome is composed of at least 118 distinct clusters corresponding to both temperate and lytic phages and representing novel genera with a large repertoire of unknown gene functions. We find that the phage community is prevalent in honey bees across space and time and targets the core members of the bee gut microbiota. The large number and high genetic diversity of the viral clusters seems to mirror the high extent of strain-level diversity in the bee gut microbiota. We isolated eight lytic phages that target the core microbiota member
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.