Evidence map›Paper›PMID 32179647›Full record

ArticleThe Journal of biological chemistry2020

Thioredoxin regulates human mercaptopyruvate sulfurtransferase at physiologically-relevant concentrations.

Pramod Kumar Yadav, Victor Vitvitsky, Sebastián Carballal, Javier Seravalli, Ruma Banerjee

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
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  5. Review
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  8. Review
  9. A Metabolic Paradigm for Hydrogen Sulfide SignalingAntioxidants & redox signaling · 2023
    Review
  10. Review
  11. Article
  12. Review
  13. Structural perspectives on HCurrent opinion in structural biology · 2021
    Review
  14. Sulfur Administration in Fe-S Cluster Homeostasis.Antioxidants (Basel, Switzerland) · 2021
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Regulation of the redox metabolome and thiol proteome by hydrogen sulfide.Critical reviews in biochemistry and molecular biology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pramod Kumar YadavDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.ORCID 0000-0003-0026-1684
Victor VitvitskyDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.
Sebastián CarballalDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600.
Javier SeravalliDepartment of Biochemistry and the Redox Biology Center, University of Nebraska, Lincoln, Nebraska 68588.
Ruma BanerjeeDepartment of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan 48109-0600 rbanerje@umich.edu.ORCID 0000-0001-8332-3275

Funding

Transsulfuration and HyperhomocysteinemiaR01HL058984 · NHLBI · UNIVERSITY OF NEBRASKA LINCOLN · PI BANERJEE, RUMA V · 1997 to 2020
$6.0M
NHLBI NIH HHS R01 HL058984
6 · The paper itself

Abstract

3-Mercaptopyruvate sulfur transferase (MPST) catalyzes the desulfuration of 3-mercaptopyruvate (3-MP) and transfers sulfane sulfur from an enzyme-bound persulfide intermediate to thiophilic acceptors such as thioredoxin and cysteine. Hydrogen sulfide (H

Indexed as

SulfurtransferasesThioredoxinsAnimalsCatalysisHEK293 CellsHep G2 CellsHumansIsoenzymesMaleMiceMice, Inbred BALB COrgan Specificity3-mercaptopyruvate sulphurtransferaseIsoenzymesSulfurtransferasesThioredoxinsallosteric regulationenzyme kineticshydrogen sulfideoxidation-reduction (redox)thioredoxin

Identifiers

PMID32179647
PMCPMC7212645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.