Evidence map›Paper›PMID 32179580›Full record

ArticleeNeuro

Localized Calcium Signaling and the Control of Coupling at Cx36 Gap Junctions.

Keith B Moore, Cheryl K Mitchell, Ya-Ping Lin, Yuan-Hao Lee, Eyad Shihabeddin, John O'Brien

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Adenosine APharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. On the Diverse Functions of Electrical Synapses.Frontiers in cellular neuroscience · 2022
    Review
  6. The Roles of Calmodulin and CaMKII in Cx36 Plasticity.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Keith B MooreRichard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Cheryl K MitchellRichard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Ya-Ping LinRichard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.
Yuan-Hao LeeRichard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.ORCID 0000-0002-2058-3317
Eyad ShihabeddinRichard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030.ORCID 0000-0002-3140-1523
John O'BrienRichard S. Ruiz, M.D. Department of Ophthalmology and Visual Science, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030 john.obrien@uth.tmc.edu.ORCID 0000-0002-0270-3442
The University of Texas Health Science Center · USThe University of Texas MD Anderson Cancer Center · US

Funding

REGULATION OF RETINAL GAP JUNCTIONSR01EY012857 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JOHN O'BRIEN · 2000 to 2026
$8.3M
UTHouston Core Center for Vision ResearchP30EY028102 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MASSEY, STEPHEN C · 2017 to 2021
$3.1M
Training Program with Universitiy of HoustonT32EY007024 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MASSEY, STEPHEN C · 1987 to 2016
$1.8M
Rod photoreceptor regeneration in a zebrafish model of Retinitis Pigmentosa.F31EY034793 · NEI · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SHIHABEDDIN, EYAD · 2023 to 2025
$82k
NEI NIH HHS F31 EY034793NEI NIH HHS P30 EY028102NEI NIH HHS R01 EY012857NEI NIH HHS T32 EY007024
6 · The paper itself

Abstract

A variety of electrical synapses are capable of activity-dependent plasticity, including both activity-dependent potentiation and activity-dependent depression. In several types of neurons, activity-dependent electrical synapse plasticity depends on changes in the local Ca

Indexed as

Calcium SignalingGap JunctionsAnimalsConnexinsGap Junction delta-2 ProteinHeLa CellsHumansConnexinsGap Junction delta-2 Proteincalcium signalingConnexin 36electrical synapseoptical imagingplasticitytracer coupling

Identifiers

PMID32179580
PMCPMC7168262
OpenAlexW3012058112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.