Evidence map›Paper›PMID 32179519›Full record

ArticleAntimicrobial agents and chemotherapy2020

Ceftobiprole Activity against Bacteria from Skin and Skin Structure Infections in the United States from 2016 through 2018.

Robert K Flamm, Leonard R Duncan, Kamal A Hamed, Jennifer I Smart, Rodrigo E Mendes, Michael A Pfaller

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.3field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Robert K FlammJMI Laboratories, North Liberty, Iowa, USA.
Leonard R DuncanJMI Laboratories, North Liberty, Iowa, USA leonard-duncan@jmilabs.com.
Kamal A HamedBasilea Pharmaceutica International Ltd., Basel, Switzerland.ORCID 0000-0003-1896-9736
Jennifer I SmartBasilea Pharmaceutica International Ltd., Basel, Switzerland.
Rodrigo E MendesJMI Laboratories, North Liberty, Iowa, USA.
Michael A PfallerJMI Laboratories, North Liberty, Iowa, USA.
JMI Laboratories · USBasilea Pharmaceutica (Switzerland) · CHUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftobiprole medocaril is an advanced-generation cephalosporin prodrug that has qualified infectious disease product status granted by the US FDA and is currently being evaluated in phase 3 clinical trials in patients with acute bacterial skin and skin structure infections (ABSSSIs) and in patients with

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcus aureusAnti-Bacterial AgentsBacteriaCephalosporinsGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsUnited StatesAnti-Bacterial AgentsceftobiproleCephalosporinsABSSSIceftobiprolecephalosporinMRSAskinSSTIsurveillance

Identifiers

PMID32179519
PMCPMC7269461
OpenAlexW3011626333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.