Evidence map›Paper›PMID 32179507›Full record

ReviewCold Spring Harbor perspectives in biology2020

Niche Cells and Signals that Regulate Lung Alveolar Stem Cells In Vivo.

Nicholas H Juul, Courtney A Stockman, Tushar J Desai

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 49 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Cellular plasticity and regenerative mechanisms in the lung.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Arrestin beta 1 Regulates Alveolar Progenitor Renewal and Lung Fibrosis.Journal of respiratory biology and translational medicine · 2024
    Article
  17. Article
  18. Durable CD4Trends in immunology · 2024
    Review
  19. Article
  20. A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Nicholas H JuulDepartment of Medicine, Division of Pulmonary, Allergy & Critical Care.
Courtney A StockmanInstitute for Stem Cell Biology & Regenerative Medicine, Stanford University School of Medicine, Stanford, California 94305, USA.
Tushar J DesaiDepartment of Medicine, Division of Pulmonary, Allergy & Critical Care.
Stanford University · US

Funding

Stanford Training Program in Lung BiologyT32HL129970 · NHLBI · STANFORD UNIVERSITY · PI CORNFIELD, DAVID N., NICOLLS, MARK ROBERT · 2016 to 2025
$3.2M
Cellular and molecular mechanisms of alveolar repairR01HL167410 · NHLBI · STANFORD UNIVERSITY · PI Tushar Jasubhai DESAI · 2023 to 2026
$2.7M
Identifying niche factors regulating distinct properties of AT2 stem cellsR01HL142549 · NHLBI · STANFORD UNIVERSITY · PI DESAI, TUSHAR JASUBHAI · 2018 to 2021
$2.2M
Graduate Training in Stem Cell Biology and Regenerative MedicineT32GM119995 · NIGMS · STANFORD UNIVERSITY · PI WEISSMAN, IRVING L. · 2017 to 2021
$2.0M
The role of Nkx2-1 in the distal lungF32HL147417 · NHLBI · STANFORD UNIVERSITY · PI JUUL, NICHOLAS HEDEMANN · 2019 to 2019
$72k
NHLBI NIH HHS F32 HL147417NHLBI NIH HHS R01 HL142549NHLBI NIH HHS R01 HL167410NHLBI NIH HHS T32 HL129970NIGMS NIH HHS T32 GM119995
6 · The paper itself

Abstract

The distal lung is a honeycomb-like collection of delicate gas exchange sacs called alveoli lined by two interspersed epithelial cell types: the cuboidal, surfactant-producing alveolar type II (AT2) and the flat, gas-exchanging alveolar type I (AT1) cell. During aging, a subset of AT2 cells expressing the canonical

Indexed as

RegenerationStem Cell NicheAgingAlveolar Epithelial CellsAnimalsHumansWnt Signaling Pathway

Identifiers

PMID32179507
PMCPMC7706567
OpenAlexW3010753891

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.