ArticleiScience2020
Genetic Control of Collective Behavior in Zebrafish.
Article in iScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Social Preference Tests in Zebrafish: A Systematic Review.Frontiers in veterinary science · 2020Pooled it
- Distinct distributed neural dynamics predict pallium-dependent social approach.Nature communications · 2026Article
- Developmental and genetic modulation of evidence integration dynamics in zebrafish sensorimotor decision-making.bioRxiv : the preprint server for biology · 2026Article
- Convergent thyroid-ATPase interactions regulate collective behavior in Danionella.Cell reports · 2026Article
- Neurogenomic and behavioral principles shape freezing dynamics and synergistic performance in Drosophila melanogaster.Nature communications · 2025Article
- Rearing in a Physically Enriched Environment Affects Shoaling and Stress Responses of Zebrafish (Veterinary sciences · 2025Article
- Tuning collective behaviour in zebrafish with genetic modification.PLoS computational biology · 2024Article
- Changes in local interaction rules during ontogeny underlie the evolution of collective behavior.iScience · 2023Article
- Behavioral analysis through the lifespan ofiScience · 2023Article
- A multi-scale review of the dynamics of collective behaviour: from rapid responses to ontogeny and evolution.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Inferring social influence in animal groups across multiple timescales.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Changes in local interaction rules during ontogeny underlie the evolution of collective behavior.bioRxiv : the preprint server for biology · 2023Article
- Social behavioral profiling by unsupervised deep learning reveals a stimulative effect of dopamine D3 agonists on zebrafish sociality.Cell reports methods · 2023Article
- Lateral line morphology, sensory perception and collective behaviour in African cichlid fish.Royal Society open science · 2023Article
- CRISPR/Cas9-Induced Inactivation of the Autism-Risk GeneInternational journal of molecular sciences · 2022Article
- Differential Gene Expression Correlates with Behavioural Polymorphism during Collective Behaviour in Cockroaches.Animals : an open access journal from MDPI · 2022Article
- The what, how, and why of naturalistic behavior.Current opinion in neurobiology · 2022Review
- Article
- Oxytocin receptors influence the development and maintenance of social behavior in zebrafish (Danio rerio).Scientific reports · 2022Article
- Multiplexed Genome Editing for Efficient Phenotypic Screening in Zebrafish.Veterinary sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many animals, including humans, have evolved to live and move in groups. In humans, disrupted social interactions are a fundamental feature of many psychiatric disorders. However, we know little about how genes regulate social behavior. Zebrafish may serve as a powerful model to explore this question. By comparing the behavior of wild-type fish with 90 mutant lines, we show that mutations of genes associated with human psychiatric disorders can alter the collective behavior of adult zebrafish. We identify three categories of behavioral variation across mutants: "scattered," in which fish show reduced cohesion; "coordinated," in which fish swim more in aligned schools; and "huddled," in which fish form dense but disordered groups. Changes in individual interaction rules can explain these differences. This work demonstrates how emergent patterns in animal groups can be altered by genetic changes in individuals and establishes a framework for understanding the fundamentals of social information processing.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.