COVID-19, ECMO, and lymphopenia: a word of caution.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

145 citing papers in PubMed, 7 syntheses or guidelines pooled it.

1. D-dimer levels and characteristics of lymphocyte subsets, cytokine profiles in peripheral blood of patients with severe COVID-19: A systematic review and meta-analysis.Frontiers in medicine · 2022
   Pooled it
2. Epidemiology and Etiopathogeny of COVID-19.Advances in experimental medicine and biology · 2021
   Pooled it
3. COVID-19 PICU guidelines: for high- and limited-resource settings.Pediatric research · 2020
   Guideline
4. Lymphopenia and neutrophilia at admission predicts severity and mortality in patients with COVID-19: a meta-analysis.Acta bio-medica : Atenei Parmensis · 2020
   Pooled it
5. Diagnostic and prognostic value of hematological and immunological markers in COVID-19 infection: A meta-analysis of 6320 patients.PloS one · 2020
   Pooled it
6. Epidemiological and Clinical Characteristics of COVID-19 in Children: A Systematic Review and Meta-Analysis.Frontiers in pediatrics · 2020
   Pooled it
7. Update of the recommendations of the Sociedade Portuguesa de Cuidados Intensivos and the Infection and Sepsis Group for the approach to COVID-19 in Intensive Care Medicine.Revista Brasileira de terapia intensiva
   Pooled it
8. Variant-divergent death: Omicron intensifies bystander T-cell apoptosis via GDF15-BCL2L13.Cell death discovery · 2026
   Article
9. The future of severe acute respiratory syndrome-cornavirus and coronavirus disease.World journal of pediatrics : WJP · 2026
   Article
10. The importance of meta-analysis to predict outcomes early in a pandemic: Extracorporeal membrane oxygenation and mortality.The American journal of emergency medicine · 2026
    Article
11. Inflammatory cytokine-primed MSC-derived extracellular vesicles ameliorate acute lung injury via enhanced immunomodulation and alveolar repair.Stem cell research & therapy · 2025
    Article
12. Mesenchymal stem cells-based therapies for severe ARDS with ECMO: a review.Intensive care medicine experimental · 2024
    Review
13. Predicting COVID-19 Re-Positive Cases in Malnourished Older Adults: A Clinical Model Development and Validation.Clinical interventions in aging · 2024
    Article
14. The role of ECMO in COVID-19 acute respiratory failure: Defining risk factors for mortality.American journal of surgery · 2023
    Article
15. Extracorporeal Membrane Oxygenation for Severe COVID-19 in Indian Scenario: A Single Center Retrospective Study.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
16. Variation in survival in patients with Coronavirus Disease 2019 supported with extracorporeal membrane oxygenation: A multi-institutional analysis of 594 consecutive patients with Coronavirus Disease 2019 supported with extracorporeal membrane oxygenation at 49 hospitals within 21 states.The Journal of thoracic and cardiovascular surgery · 2023
    Review
17. The Evaluation of Hematological Parameters and Their Correlation with Disease Prognosis in COVID-19 Disease in Iran.International journal of hematology-oncology and stem cell research · 2023
    Article
18. Mortality rates of severe COVID-19-related respiratory failure with and without extracorporeal membrane oxygenation in the Middle Ruhr Region of Germany.Scientific reports · 2023
    Article
19. Very Low Driving-Pressure Ventilation in Patients With COVID-19 Acute Respiratory Distress Syndrome on Extracorporeal Membrane Oxygenation: A Physiologic Study.Journal of cardiothoracic and vascular anesthesia · 2023
    Article
20. Parameters to Predict the Outcome of Severe and Critical COVID-19 Patients when Admitted to the Hospital.Journal of clinical medicine · 2023
    Article

85 more citing papers are in PubMed but not listed here.

Corrections and comments

• Comment on
  Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study.2020

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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