Evidence map›Paper›PMID 32178648›Full record

Trial reportBMC nephrology2020

Effect of a pedometer-based walking intervention on body composition in patients with ESRD: a randomized controlled trial.

Anoop Sheshadri, Piyawan Kittiskulnam, Jennifer C Lai, Kirsten L Johansen

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02623348 (Use of Pedometers to Measure and Increase Walking Among Patients With ESRD), which is not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02623348 nacompletednot on this map

Use of Pedometers to Measure and Increase Walking Among Patients With ESRD

TypeinterventionalSponsorUniversity of California, San FranciscoRan2015 to 2018Enrolled60ConditionsEnd-stage Renal DiseaseArmspedometer
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Exercise training for adults undergoing maintenance dialysis.The Cochrane database of systematic reviews · 2022
    Pooled it
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Anoop SheshadriDivision of Nephrology, Department of Medicine, University of California, San Francisco, USA. Anoop.Sheshadri@ucsf.edu.
Piyawan KittiskulnamDivision of Internal Medicine-Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Jennifer C LaiDivision of Gastroenterology/Hepatology, Department of Medicine, University of California, San Francisco, USA.
Kirsten L JohansenDivision of Nephrology, Hennepin County Medical Center, Minneapolis, MN, USA.
University of California, San Francisco · USChulalongkorn University · THHennepin County Medical Center · US

Funding

The spectrum of cognitive impairment including Alzheimer’s Disease and Related Dementias after liver transplantationR01AG059183 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Jennifer C. Lai · 2018 to 2026
$9.9M
Prevalence and Impact of Frailty among Dialysis PatientsK24DK085153 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHANSEN, KIRSTEN L. · 2010 to 2021
$1.5M
Pedometers and Exercise in DialysisF32DK111154 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHESHADRI, ANOOP · 2016 to 2018
$145k
NIA NIH HHS R01 AG059183NIDDK NIH HHS F32 DK111154NIDDK NIH HHS K24 DK085153
6 · The paper itself

Abstract

backgroundA randomized trial of a pedometer-based intervention with weekly activity goals led to a modest increase in step count among dialysis patients. In a secondary analysis, we investigated the effect of this intervention on body composition.

methodsSixty dialysis patients were randomized to standard care or a 6-month program consisting of 3 months of pedometers and weekly step count targets and 3 months of post-intervention follow-up. We obtained bioelectrical impedance spectroscopy (BIS) data on 54 of these patients (28 control, 26 intervention) and used linear mixed-modeling (adjusted for sex and dialysis modality) to estimate differences in change in total-body muscle mass (TBMM) adjusted for height

resultsThe median age of participants was 57.5 years (53-66), and 76% were men. At baseline, there was no significant difference between groups in age, BMI, race, or body composition, but there were more men in the intervention group. After 3 months, patients in the intervention group increased their average daily steps by 2414 (95% CI 1047, 3782) more than controls (p < 0.001), but there were no significant differences in body composition. However, at 6 months, participants in the intervention had a significantly greater increase from baseline in TBMM of 0.7 kg/m

conclusionA pedometer-based intervention resulted in greater decreases in fat mass with relative preservation of muscle mass, leading to a greater decrease in BMI over time compared with patients not in the intervention. These differences were driven as much by worsening in the control group as by improvement in the intervention group. Step counts had a dose-response relationship with decrease in fat mass.

trial registrationClinicalTrials.gov (NCT02623348). 02 December 2015.

Indexed as

Body CompositionRenal DialysisActigraphyAgedBody Fat DistributionBody Mass IndexFemaleFitness TrackersHumansKidney Failure, ChronicMaleMiddle AgedMuscular AtrophyWalkingBody composition, fat mass, muscle massDialysisPhysical activitySarcopenia

Identifiers

PMID32178648
PMCPMC7074998
OpenAlexW3010759123

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.