Evidence map›Paper›PMID 32178473›Full record

ArticleMolecules (Basel, Switzerland)2020

Psoralen Derivatives as Inhibitors of

Kaja Rožman, Evan M Alexander, Eva Ogorevc, Krištof Bozovičar, Izidor Sosič, Courtney C Aldrich, Stanislav Gobec

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Identification of NewMolecules (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kaja RožmanUniversity of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.
Evan M AlexanderDepartment of Medicinal Chemistry, University of Minnesota, 308 Harvard Street Southeast, Minneapolis, MN 55455, USA.
Eva OgorevcUniversity of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.
Krištof BozovičarUniversity of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.ORCID 0000-0003-0025-1734
Izidor SosičUniversity of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.ORCID 0000-0002-3370-4587
Courtney C AldrichDepartment of Medicinal Chemistry, University of Minnesota, 308 Harvard Street Southeast, Minneapolis, MN 55455, USA.
Stanislav GobecUniversity of Ljubljana, Faculty of Pharmacy, Aškerčeva 7, SI-1000 Ljubljana, Slovenia.
University of Ljubljana · SIUniversity of Minnesota · US

Funding

Javna Agencija za Raziskovalno Dejavnost RS P1-0208Ministry of Education, Science and Sports of Republic of Slovenia C3330-17-529028 Raziskovalci-2.0-UL-FFA-529028
6 · The paper itself

Abstract

Protein degradation is a fundamental process in all living organisms. An important part of this system is a multisubunit, barrel-shaped protease complex called the proteasome. This enzyme is directly responsible for the proteolysis of ubiquitin- or pup-tagged proteins to smaller peptides. In this study, we present a series of 92 psoralen derivatives, of which 15 displayed inhibitory potency against the

Indexed as

FicusinHumansMycobacterium tuberculosisProteasome InhibitorsProteolysisTuberculosisUbiquitinUbiquitinsFicusinProteasome InhibitorsUbiquitinUbiquitinsMycobacterium tuberculosisnonpeptidic proteasome inhibitorsproteasomeprotein degradationpsoralens

Identifiers

PMID32178473
PMCPMC7144120
OpenAlexW3012351017

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.