Evidence map›Paper›PMID 32178439›Full record

ArticleInternational journal of molecular sciences2020

Dopaminergic Modulation of Orofacial Mechanical Hypersensitivity Induced by Infraorbital Nerve Injury.

Hiroharu Maegawa, Nayuka Usami, Chiho Kudo, Hiroshi Hanamoto, Hitoshi Niwa

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Activation of mu-opioid receptors slows pacemaking in hypothalamic A11 dopamine neurons.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hiroharu MaegawaDepartment of Dental Anesthesiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.ORCID 0000-0001-8331-546X
Nayuka UsamiDepartment of Dental Anesthesiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.
Chiho KudoDepartment of Dental Anesthesiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.
Hiroshi HanamotoDepartment of Dental Anesthesiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.
Hitoshi NiwaDepartment of Dental Anesthesiology, Osaka University Graduate School of Dentistry, Suita, Osaka 565-0871, Japan.
Osaka Dental University · JP

Funding

Japan Society for the Promotion of Science 17K17242, 19K19192
6 · The paper itself

Abstract

While the descending dopaminergic control system is not fully understood, it is reported that the hypothalamic A11 nucleus is its principle source. To better understand the impact of this system, particularly the A11 nucleus, on neuropathic pain, we created a chronic constriction injury model of the infraorbital nerve (ION-CCI) in rats. ION-CCI rats received intraperitoneal administrations of quinpirole (a dopamine D2 receptor agonist). ION-CCI rats received microinjections of quinpirole, muscimol [a gamma-aminobutyric acid type A (GABA

Indexed as

AnimalsCranial NervesDopamineExtracellular Signal-Regulated MAP KinasesFacial Nerve InjuriesGABA-A Receptor Agonistsgamma-Aminobutyric AcidHyperalgesiaHypothalamusMaleMuscimolNeuralgiaOxidopaminePain MeasurementPain ThresholdPhosphorylationDopamineExtracellular Signal-Regulated MAP KinasesGABA-A Receptor Agonistsgamma-Aminobutyric AcidMuscimolOxidopamineQuinpiroleReceptors, Dopamine D26-hydroxydopamineA11 nucleuschronic constriction injurydopamine receptorinfraorbital nervemuscimolphosphorylated extracellular signal-regulated kinase (pERK)quinpiroletrigeminal spinal subnucleus caudalis

Identifiers

PMID32178439
PMCPMC7139594
OpenAlexW3012452085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.