Evidence map›Paper›PMID 32178423›Full record

ArticlePharmaceutics2020

Reversible Cross-Linked Mixed Micelles for pH Triggered Swelling and Redox Triggered Degradation for Enhanced and Controlled Drug Release.

Di Xiong, Liyang Wen, Shiyuan Peng, Jianchang Xu, Lijuan Zhang

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. UV-Triggered Cascading Degradation of Silicone Elastomer via Self-Fluoride Amplification.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Synthetic organic materials for targeting immunotherapies to lymph nodes.Chemistry of materials : a publication of the American Chemical Society · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Smart Nanomaterials for Biomedical Applications-A Review.Nanomaterials (Basel, Switzerland) · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Di XiongSchool of Chemical Engineering, Xiangtan University, Xiangtan 411105, China.ORCID 0000-0003-2510-8870
Liyang WenSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Shiyuan PengSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Jianchang XuSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
Lijuan ZhangSchool of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640, China.
South China University of Technology · CNXiangtan University · CN

Funding

National Natural Science Foundation of China 21776101Natural Science Foundation of Hunan Province 2019JJ50584PhD Research Startup Foundation of Xiangtan University 18QDZ21Scientific Research Foundation of Hunan Provincial Education Department 19C1757
6 · The paper itself

Abstract

Good stability and controlled drug release are important properties of polymeric micelles for drug delivery. A good candidate for drug delivery must have outstanding stability in a normal physiological environment, followed with low drug leakage and side effects. Moreover, the chemotherapeutic drug in the micellar core should also be quickly and "on-demand" released in the intracellular microenvironment at the tumor site, which is in favor of overcoming multidrug resistance (MDR) effects of tumor cells. In this work, a mixed micelle was prepared by the simple mix of two amphiphilic copolymers, namely PCL-SS-P(PEGMA-

Indexed as

drug deliverymixed micellesreversible cross-linkstimulus-responsive

Identifiers

PMID32178423
PMCPMC7151195
OpenAlexW3011157906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.