ArticleJournal of clinical medicine2020
Bioactivity and Physico-Chemical Properties of Dental Composites Functionalized with Nano- vs. Micro-Sized Bioactive Glass.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 63 citations in OpenAlex.
- How does thermocycling affect the surface properties of ion-releasing bulk‑fill resin composites?European journal of oral sciences · 2026Article
- Evaluation of the Effect of Different Light-Curing Protocols on the Microhardness of Contemporary Bulk-Fill Resin Composites.Polymers · 2025Article
- Surface Micromorphology of Experimental Composites Doped with Bioactive Glass After Different Storage Times.Journal of functional biomaterials · 2025Article
- Effect of Bioactive Glass on Microshear Bond Strength of Composite Resin to Dentin Using a Universal Adhesive with Different Application Modes and Storage Times.Frontiers in dentistry · 2025Article
- A review of new generation of dental restorative resin composites with antibacterial, remineralizing and self-healing capabilities.Discover nano · 2024Review
- Water-Induced Changes in Experimental Resin Composites Functionalized with Conventional (45S5) and Customized Bioactive Glass.Journal of functional biomaterials · 2023Article
- Ceramic Nanomaterials in Caries Prevention: A Narrative Review.Nanomaterials (Basel, Switzerland) · 2022Review
- Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives.Nanomaterials (Basel, Switzerland) · 2022Article
- A Narrative Review of Bioactive Glass-Loaded Dental Resin Composites.Journal of functional biomaterials · 2022Review
- Premixed Calcium Silicate-Based Root Canal Sealer Reinforced with Bioactive Glass Nanoparticles to Improve Biological Properties.Pharmaceutics · 2022Article
- Effect of adhesive coating on calcium, phosphate, and fluoride release from experimental and commercial remineralizing dental restorative materials.Scientific reports · 2022Article
- Marginal Adaptation of Flowable vs Sonically Activated or Preheated Resin Composites in Cervical Lesions.The journal of adhesive dentistry · 2022Article
- Physical/Mechanical and Antibacterial Properties of Orthodontic Adhesives Containing Calcium Phosphate and Nisin.Journal of functional biomaterials · 2021Article
- Experimental Bioactive Glass-Containing Composites and Commercial Restorative Materials: Anti-Demineralizing Protection of Dentin.Biomedicines · 2021Article
- Polymerization kinetics of experimental resin composites functionalized with conventional (45S5) and a customized low-sodium fluoride-containing bioactive glass.Scientific reports · 2021Article
- Short- and Long-Term Dentin Bond Strength of Bioactive Glass-Modified Dental Adhesives.Nanomaterials (Basel, Switzerland) · 2021Article
- Anti-demineralizing protective effects on enamel identified in experimental and commercial restorative materials with functional fillers.Scientific reports · 2021Article
- Nanoparticles of Bioactive Glass Enhance Biodentine Bioactivity on Dental Pulp Stem Cells.Materials (Basel, Switzerland) · 2021Article
- Resin-Based Sealant with Bioactive Glass and Zwitterionic Material for Remineralisation and Multi-Species Biofilm Inhibition.Nanomaterials (Basel, Switzerland) · 2020Article
- New Ways to Disinfect and Fill Dental Hard Tissues.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioactive resin composites can contribute to the prevention of secondary caries, which is one of the main reasons for failure of contemporary dental restorations. This study investigated the effect of particle size of bioactive glass 45S5 on chemical and physical composite properties. Four experimental composites were prepared by admixing the following fillers into a commercial flowable composite: (1) 15 wt% of micro-sized bioactive glass, (2) 15 wt% of nano-sized bioactive glass, (3) a combination of micro- (7.5 wt%) and nano-sized (7.5 wt%) bioactive glass, and (4) 15 wt% of micro-sized inert barium glass. Hydroxyapatite precipitation and pH rise in phosphate-buffered saline were evaluated during 28 days. Degree of conversion and Knoop microhardness were measured 24 h after specimen preparation and after 28 days of phosphate-buffered saline immersion. Data were analyzed using non-parametric statistics (Kruskal-Wallis and Wilcoxon tests) at an overall level of significance of 5%. Downsizing the bioactive glass particles from micro- to nano-size considerably improved their capability to increase pH. The effect of nano-sized bioactive glass on degree of conversion and Knoop microhardness was similar to that of micro-sized bioactive glass. Composites containing nano-sized bioactive glass formed a more uniform hydroxyapatite layer after phosphate-buffered saline immersion than composites containing exclusively micro-sized particles. Partial replacement of nano- by micro-sized bioactive glass in the hybrid composite did not impair its reactivity, degree of conversion (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.