Evidence map›Paper›PMID 32178261›Full record

ArticleFoods (Basel, Switzerland)2020

Bioavailability of Melatonin from Lentil Sprouts and Its Role in the Plasmatic Antioxidant Status in Rats.

Miguel Rebollo-Hernanz, Yolanda Aguilera, Teresa Herrera, L Tábata Cayuelas, Montserrat Dueñas, Pilar Rodríguez-Rodríguez, David Ramiro-Cortijo, Silvia M Arribas, María A Martín-Cabrejas

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 46 citations in OpenAlex.

  1. The Germination Paradox in Sorghum: A Review.Foods (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Mediterranean Diet and Melatonin: A Systematic Review.Antioxidants (Basel, Switzerland) · 2023
    Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Miguel Rebollo-HernanzDepartment of Agricultural Chemistry and Food Science, School of Science, Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0003-1034-1290
Yolanda AguileraDepartment of Agricultural Chemistry and Food Science, School of Science, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Teresa HerreraInstitute of Food Science Research, CIAL (UAM-CSIC), 28049 Madrid, Spain.
L Tábata CayuelasInstitute of Food Science Research, CIAL (UAM-CSIC), 28049 Madrid, Spain.
Montserrat DueñasGrupo de Investigación en Polifenoles, Unidad de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Salamanca, Campus Miguel de Unamuno, 37007 Salamanca, Spain.ORCID 0000-0001-6000-9259
Pilar Rodríguez-RodríguezDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
David Ramiro-CortijoDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.ORCID 0000-0001-7442-1586
Silvia M ArribasDepartment of Physiology, School of Medicine, Universidad Autónoma de Madrid, 28029 Madrid, Spain.
María A Martín-CabrejasDepartment of Agricultural Chemistry and Food Science, School of Science, Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0001-9834-639X
Instituto de Investigación en Ciencias de la Alimentación · ESUniversidad Autónoma de Madrid · ESUniversidad de Salamanca · ES

Funding

Ministerio de Ciencia, Innovación y Universidades FPU15/04238UAM-Banco Santander 2013/EEUU/02
6 · The paper itself

Abstract

Melatonin is a multifunctional antioxidant neurohormone found in plant foods such as lentil sprouts. We aim to evaluate the effect of lentil sprout intake on the plasmatic levels of melatonin and metabolically related compounds (plasmatic serotonin and urinary 6-sulfatoxymelatonin), total phenolic compounds, and plasmatic antioxidant status, and compare it with synthetic melatonin. The germination of lentils increases the content of melatonin. However, the phenolic content diminished due to the loss of phenolic acids and flavan-3-ols. The flavonol content remained unaltered, being the main phenolic family in lentil sprouts, primarily composed of kaempferol glycosides. Sprague Dawley rats were used to investigate the pharmacokinetic profile of melatonin after oral administration of a lentil sprout extract and to evaluate plasma and urine melatonin and related biomarkers and antioxidant capacity. Melatonin showed maximum concentration (45.4 pg/mL) 90 min after lentil sprout administration. The plasmatic melatonin levels increased after lentil sprout intake (70%,

Indexed as

antioxidant statusbioavailabilitylentil sproutsmelatoninpharmacokineticsphenolic compounds

Identifiers

PMID32178261
PMCPMC7143261
OpenAlexW3011773193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.