Evidence map›Paper›PMID 32176669›Full record

ArticleJournal of pediatric rehabilitation medicine2020

In-clinic event related potentials after sports concussion: A 4-year study.

Gerald Clayton, Natalie Davis, Adam Holliday, David Joffe, David S Oakley, Francis X Palermo, Sourav Poddar, Miguel Rueda

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of pediatric rehabilitation medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gerald ClaytonSchool of Medicine, University of Colorado, Aurora, CO, USA.
Natalie DavisDepartment of Athletics, University of Colorado, Boulder, CO, USA.
Adam HollidayDepartment of Athletics, University of Colorado, Boulder, CO, USA.
David JoffeWAVi Research, Boulder, CO, USA.
David S OakleyWAVi Research, Boulder, CO, USA.
Francis X PalermoSchool of Medicine, University of Colorado, Aurora, CO, USA.
Sourav PoddarSchool of Medicine, University of Colorado, Aurora, CO, USA.
Miguel RuedaDepartment of Athletics, University of Colorado, Boulder, CO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeElectrophysiological event-related potentials (ERP's) have been reported to change after concussion. The objective of this study is to use a simple 2-tone auditory P300 ERP in routine clinical settings to measure changes from baseline after concussion and to determine if these changes persist at return to play when other standard measures have normalized.

methodsThree-hundred sixty-four (364) student athletes, aged 17-23 years, participating in contact sports were tracked over consecutive years. In this blinded study P300, plus physical reaction times and Trail Making tests, were collected alongside standard clinical evaluations. Changes in these measures after concussion were compared to clinical outcomes over various stages of post-injury recovery.

resultsConcussed players experienced significant reaction time and/or P300 amplitude changes compared to pre-concussion baseline measurements (p< 0.005). P300 changes persisted in 38% of the players after standard measures, including reaction times, had cleared. Many of those players slow to normalize were part of the sub-concussive symptom group and/or appeared more prone to repeat concussions.

conclusionThese data suggest significant P300 amplitude changes after concussion that are quantifiable and consistent. These changes often normalized slower than other standard assessments. More data are needed to determine if slow normalization relates to sub-concussive or repeated events.

Indexed as

AdolescentAdultAthletic InjuriesBrain ConcussionEvoked Potentials, AuditoryFemaleHumansMaleNeuropsychological TestsYoung AdultConcussionelectroencephalogramevent related potentialsP300reaction timereturn to playsportstrail making

Identifiers

PMID32176669
PMCPMC7242851

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.