Evidence map›Paper›PMID 32176482›Full record

ArticleACS chemical neuroscience2020

Innovative IgG Biomarkers Based on Phage Display Microbial Amyloid Mimotope for State and Stage Diagnosis in Alzheimer's Disease.

Laura M De Plano, Santina Carnazza, Domenico Franco, Maria Giovanna Rizzo, Sabrina Conoci, Salvatore Petralia, Alessandra Nicoletti, Mario Zappia, Michela Campolo, Emanuela Esposito and 2 more

Abstract read
In one paragraph

Article in ACS chemical neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Amyloid-Related Imaging Abnormality (ARIA) Beyond the APOE-ε4 Allele.Chronic diseases and translational medicine · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Novel Serum-Based Diagnosis of Alzheimer's Disease Using an Advanced Phage-Based Biochip.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  9. Review
  10. Article
  11. Applications of CRISPR-Cas9 in Alzheimer's Disease and Related Disorders.International journal of molecular sciences · 2022
    Review
  12. Review
  13. Review
  14. Role of Phage Capsid in the Resistance to UV-C Radiations.International journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Laura M De PlanoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Santina CarnazzaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Domenico FrancoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Maria Giovanna RizzoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Sabrina ConociSTmicroelectronics, Stradale Primosole, 50, 95121 Catania, Italy.ORCID 0000-0002-5874-7284
Salvatore PetraliaSTmicroelectronics, Stradale Primosole, 50, 95121 Catania, Italy.ORCID 0000-0001-5692-1130
Alessandra NicolettiNeurology Clinic, Department "G.F. Ingrassia", Section of Neurosciences, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.
Mario ZappiaNeurology Clinic, Department "G.F. Ingrassia", Section of Neurosciences, University of Catania, Via Santa Sofia 78, 95123 Catania, Italy.
Michela CampoloDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Emanuela EspositoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Salvatore CuzzocreaDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.
Salvatore P P GuglielminoDepartment of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale F. Stagno d'Alcontres 31, 98166 Messina, Italy.ORCID 0000-0002-0401-6400

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An innovative approach to identify new conformational antigens of Aβ

Indexed as

Alzheimer DiseaseAmyloidAmyloid beta-PeptidesAmyloidogenic ProteinsBacteriophagesBiomarkersHumansImmunoglobulin GPeptide FragmentsAmyloidAmyloid beta-PeptidesAmyloidogenic ProteinsBiomarkersImmunoglobulin GPeptide FragmentsAD state and stage progression screeningamyloid conformational epitopesautoantibody detectionAβ1−42 cytotoxicity inhibitionfibril disaggregationPhage display double binding selection

Identifiers

PMID32176482
PMCPMC7997372

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.