ArticleInvestigative ophthalmology & visual science2020
The Morphological Relationship Between Dome-Shaped Macula and Myopic Retinoschisis: A Cross-sectional Study of 409 Highly Myopic Eyes.
Article in Investigative ophthalmology & visual science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed, 33 citations in OpenAlex.
- Degradable Suture-Free Scaffold to Induce Therapeutic Ridge Formation and to Control Eye Elongation: A Potential Treatment for Pathological Myopia.Translational vision science & technology · 2026Article
- Photoreceptor cone loss is associated with decreased deep retinal vessel density and impaired retinal sensitivity in high myopia.The British journal of ophthalmology · 2025Article
- Clinical characteristics of dome-shaped macula in mild myopic or non-myopic eyes.Eye (London, England) · 2025Article
- Comparison of the effectiveness of vitrectomy with silicone oil or perfluoropropane tamponade for myopic foveoschisis with foveal detachment.Frontiers in medicine · 2025Article
- Myopic traction maculopathy in fovea-involved myopic chorioretinal atrophy.Eye (London, England) · 2024Article
- Semi-Automated Analysis of Dome-Shaped Macula in Preterm and Full-Term Infants Using Handheld Swept-Source Optical Coherence Tomography.Investigative ophthalmology & visual science · 2024Observational
- Choroidal vascular changes in early-stage myopic maculopathy from deep learning choroidal analysis: a hospital-based SS-OCT study.Eye and vision (London, England) · 2024Article
- Multimodal Analysis on Clinical Characteristics of the Advanced Stage in Myopic Traction Maculopathy.Ophthalmology and therapy · 2023Article
- Correlation of Visual Acuity and Outer Retinal Thickness in Myopic Atrophic Maculopathy: A Retrospective Review.Ophthalmology and therapy · 2023Article
- A Genome-Wide Association Study for Susceptibility to Axial Length in Highly Myopic Eyes.Phenomics (Cham, Switzerland) · 2023Article
- The characteristics of dome-shaped macula in Chinese children aged 4-6 years using optical coherence tomography angiography.BMC ophthalmology · 2023Article
- Natural course of myopic traction maculopathy and factors influencing progression and visual acuity.BMC ophthalmology · 2021Observational
- Dome-shaped maculopathy: a review.Eye (London, England) · 2021Review
- Multimodal Imaging-Based Phenotyping of a Singaporean Hospital-Based Cohort of High Myopia Patients.Frontiers in medicine · 2021Article
- Characteristics of Myopic Traction Maculopathy in the Aier-SERI High Myopia Adult Cohort Study.Ophthalmology scienceArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The purpose of this study was to analyze the clinical features of dome-shaped macula (DSM) in highly myopic eyes and its morphological relationship with myopic retinoschisis (MRS). Methods: In this cross-sectional study, 409 eyes of 409 patients with high myopia who had spectral-domain optical coherence tomography (OCT) examinations were included. The associations of DSM with the distribution of MRS and ocular biometry were evaluated. Results: Of 409 eyes, DSM was detected in 64 eyes (15.6%). The eyes with DSM were more myopic (-18.8 ± 3.9 vs. -13.4 ± 5.9; P < 0.001) and had longer axial length (31.7 ± 2.4 vs. 29.5 ± 2.5; P < 0.001) compared with those without DSM. A higher rate of extrafoveal retinoschisis (35.9% vs. 9.6%; P < 0.001) and a lower rate of foveoschisis (10.9% vs. 26.1%; P = 0.01) were detected in the eyes with DSM compared with those without DSM. In the eyes with DSM, MRS was detected in 30 eyes (46.9%). MRS predominantly affected the extrafoveal area (76.7%), especially the base of the dome (82.6%). The extrafoveal retinoschisis was most frequently distributed in the superior quadrant (52.2%). None of the eyes with DSM displayed fovea-only retinoschisis. The ratio of the height and width of the macular bulge was higher in eyes with MRS than those without MRS (0.05 vs. 0.04; P = 0.001). Conclusions: A DSM is found in highly myopic eyes with a longer axial length. MRS in eyes with DSM is more likely to affect the extrafoveal area, especially the base of the dome. A steeper macular bulge is associated with the occurrence of MRS.
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