Evidence map›Paper›PMID 32176226›Full record

ArticleAllergologie select2019

ARIA guideline 2019: treatment of allergic rhinitis in the German health system.

Ludger Klimek, Claus Bachert, Oliver Pfaar, Sven Becker, Thomas Bieber, Randolph Brehler, Roland Buhl, Ingrid Casper, Adam Chaker, Wolfgang Czech and 41 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergologie select, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Comparison of Allergic Rhinitis Treatments on Utilities and Quality of Life: A MASK-air Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Patient preferences in the treatment of children with pollen-related allergic rhinitis.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2026
    Article
  14. Assessment of the Effectiveness of Allergic Rhinitis Medications Using a Target Trial Emulation Approach Based on Mobile Health Data.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Cost-effectiveness of antihistaminics in adults' patients with allergic rhinitis.Cost effectiveness and resource allocation : C/E · 2025
    Article
  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

51 authors.

Ludger KlimekCenter of Rhinology and Allergology, Wiesbaden, Germany.
Claus BachertUpper Airways Research Laboratory and Department of Oto-Rhino-Laryngology, Ghent University and Ghent, University Hospital, Ghent, Belgium, Division of ENT Diseases, CLINTEC, Karolinska Institute, University of Stockholm, Stockholm, Sweden.
Oliver PfaarDepartment of Otorhinolaryngology, Head and Neck, Surgery, Section of Rhinology and Allergy, University, Hospital Marburg, Philipps-Universität Marburg,Marburg, Germany.
Sven BeckerDepartment of Otolaryngology, Head and Neck Surgery, University of Tübingen, Tübingen, Germany.
Thomas BieberDepartment of Dermatology and Allergy, University of Bonn, Bonn, Germany, Christine Kühne-Center for Allergy Research and Education (CK-CARE) Davos-Augsburg-Bonn-St Gallen-Zürich, St. Gallen, Switzerland.
Randolph BrehlerDepartment of Allergy, Occupational Dermatology and Environmental Medicine, Universitätsklinikum Münster, Münster, Germany.
Roland BuhlPulmonary Department,Mainz University Hospital,Mainz, Germany.
Ingrid CasperCenter of Rhinology and Allergology, Wiesbaden, Germany.
Adam ChakerDepartment of Otolaryngology and Center for Allergy and Environment (ZAUM), Klinikum rechts der Isar, Technical University of Munich and Helmholtz Center Munich, Munich, Germany.
Wolfgang CzechDepartment of Dermatology, University of Freiburg, Freiburg, Germany.
Jörg FischerDepartment of Dermatology, Eberhard Karls University, Tübingen, Tübingen, Germany.
Thomas FuchsDepartment of Dermatology, Venereology, and Allergology, University Medical Center, Georg August University, Göttingen, Germany.
Michael GerstlauerPediatric Pneumology and Allergology Unit, Medical University of Augsburg, Augsburg, Germany.
Karl HörmannDepartment of Otorhinolaryngology, Mannheim University Hospital, Mannheim, Germany.
Thilo JakobDepartment of Dermatology and Allergology, University Medical Center Gießen and Marburg, Campus Gießen, Justus-Liebig-University, Gießen, Germany.
Kirsten JungGroup Practice for Dermatology, Erfurt, Germany.
Matthias V KoppClinic of Pediatric and Adolescent Medicine, Airway Research Center North (ARCN), Member of the German Lung Center (DZL), Lübeck University, Lübeck, Germany.
Vera MahlerMedical Faculty, Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Germany.
Hans MerkDepartment of Dermatology and Allergology, University Hospital, RWTH Aachen University, Aachen, Germany.
Norbert MülleneisenAsthma and Allergy Centre, Leverkusen, Germany.
Katja NematDepartment of Pediatrics, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.
Uta RabeDepartment of Allergology, Johanniter-Krankenhaus im Fläming Treuenbrietzen GmbH, Treuenbrietzen, Germany.
Johannes RingDepartment and Outpatient Clinic for Dermatology and Allergology am Biederstein, Technical University of Munich, Munich, Germany and Christine Kühne Center for Allergy Research and Education (CK-Care), Davos, Switzerland.
Joachim SalogaDepartment of Dermatology, University Medical Center Mainz,Mainz, Germany.
Wolfgang SchlenterFormer Head ENT - Department, Katharina-Kasper-Kliniken, Marienkrankenhaus, c/o University Hospital, Frankfurt, Germany.
Carsten Schmidt-WeberCenter for Allergy and Environment (ZAUM), Member of the German Center of Lung Research (DZL) and the Inflammation and Immunology Helmholtz Initiative, Technical University of Munich and Helmholtz Center Munich, Munich, Germany.
Holger SeyfarthPharmacy Association in Hesse, Offenbach, Germany.
Annette SperlCenter of Rhinology and Allergology, Wiesbaden, Germany.
Thomas SpindlerAllergy Campus Davos, Hochgebirgsklinik Davos dpt. Pediatrics, Davos, Switzerland.
Petra StaubachDepartment of Dermatology, University Medical Center Mainz,Mainz, Germany.
Sebastian StriethDepartment of Otolaryngology, University Medical Center Mainz, Mainz, Germany.
Regina TreudlerDepartment of Dermatology, Venereology and Allergology, LICA - Leipzig Comprehensive Allergy Center, University of Leipzig, Leipzig, Germany.
Christian VogelbergDepartment of Pediatric Pneumology and Allergology, University Hospital Carl Gustav Carus, Technical University of Dresden, Dresden, Germany.
Andrea WallrafenGerman Allergy and Asthma Association, Mönchengladbach, Germany.
Wolfgang WehrmannDermatology Group Practice,Münster, Germany.
Holger WredeHerford, North Rhine-Westphalia, Germany.
Torsten ZuberbierDepartment of Dermatology and Allergy, Allergie-Centrum - Charité, Charité - Universitätsmedizin, Berlin, Berlin, Germany.
Anna BedbrookMACVIA-France, Montpellier, France.
Giorgio W CanonicaAllergy Section, Allergy and Respiratory Diseases, DIMI, University of Genoa, Genoa, Italy.
Victoria CardonaDepartment of Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
Thomas B CasaleDivision of Allergy and Immunology, University of South Florida, Tampa, FL, USA.
Wienczylawa CzarlewskiMedical Consulting Czarlewski, Levallois, France.
Wytske J FokkensDepartment Otorhinolaryngologie, Academic Medical Centers, Amsterdam, The Netherlands.
Eckard HamelmannChildren's Center, Protestant Hospital Bethel, University Bielefeld, Bielefeld Germany.
Marek JutelDepartment of Clinical Immunology, Wroclaw Medical University, Wroclaw, Poland and ALL-MED Medical Research Institute, Wroclaw, Poland.
Désirée Larenas-LinnemannHospitalMédica Sur, México City, Mexico.
Joaquim MullolUnitat de Rinologia i Clínica de l'Olfacte, Servei d'ORL, Hospital Clínic, Clinical and Experimental Respiratory Immunoallergy, IDIBAPS, University of Barcelona, Barcelona, Spain.
Nikolaos G PapadopoulosDepartment of Allergy, 2.
Sanna Toppila-SalmiPediatric Clinic, University of Athens, Athens, Greece.
Thomas WerfelHaartman Institute, University of Helsinki, Helsinki, Finland.
Jean BousquetDepartment of Dermatology and Allergy, Allergie-Centrum - Charité, Charité - Universitätsmedizin, Berlin, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe number of patients affected by allergies is increasing worldwide. The resulting allergic diseases are leading to significant costs for health care and social systems. Integrated care pathways are needed to enable comprehensive care within the national health systems. The ARIA (Allergic Rhinitis and its Impact on Asthma) initiative develops internationally applicable guidelines for allergic respiratory diseases.

methodsARIA serves to improve the care of patients with allergies and chronic respiratory diseases. In collaboration with other international initiatives, national associations and patient organizations in the field of allergies and respiratory diseases, real-life integrated care pathways have been developed for a digitally assisted, integrative, individualized treatment of allergic rhinitis (AR) with comorbid asthma. In the present work, these integrated care pathways have been adapted to the German situation and health system.

resultsThe present ICP (integrated care pathway) guideline covers key areas of the care of AR patients with and without asthma. It includes the views of patients and other healthcare providers. DISCUSSION: A comprehensive ICP guideline can reflect real-life care better than traditional guideline models.

Indexed as

allergen-specific immunotherapyallergic asthmaallergic diseaseshealth care systemintegrated care pathway

Identifiers

PMID32176226
PMCPMC7066682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.