Evidence map›Paper›PMID 32175909›Full record

Observational studyJournal of medical Internet research2020

Adherence to Prescribed E-Diary Recording by Patients With Seasonal Allergic Rhinitis: Observational Study.

Marco Di Fraia, Salvatore Tripodi, Stefania Arasi, Stephanie Dramburg, Sveva Castelli, Danilo Villalta, Francesca Buzzulini, Ifigenia Sfika, Valeria Villella, Ekaterina Potapova and 7 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of medical Internet research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 49 citations in OpenAlex.

  1. Patient adherence and response time in electronic patient-reported outcomes: insights from three longitudinal clinical trials.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Trial
  2. Early Detection of Lower Adherence to Long-Term e-Diary Recording: A Checkpoint to Target Early Educational Intervention in Seasonal Allergic Rhinitis?Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2026
    Observational
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Applicability of the MASK-AirInternational journal of molecular sciences · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Marco Di FraiaDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0002-9679-8859
Salvatore TripodiPediatric Allergology Unit, Sandro Pertini Hospital, Rome, Italy.ORCID 0000-0003-2517-3285
Stefania ArasiDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0002-8135-0568
Stephanie DramburgDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0002-9303-3260
Sveva CastelliDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0001-7660-5354
Danilo VillaltaDepartment of Immunology-Allergy, Santa Maria degli Angeli Hospital, Pordenone, Italy.ORCID 0000-0003-4085-9218
Francesca BuzzuliniDepartment of Immunology-Allergy, Santa Maria degli Angeli Hospital, Pordenone, Italy.ORCID 0000-0002-1498-6443
Ifigenia SfikaPediatric Allergology Unit, Sandro Pertini Hospital, Rome, Italy.ORCID 0000-0003-2365-0498
Valeria VillellaPediatric Allergology Unit, Sandro Pertini Hospital, Rome, Italy.ORCID 0000-0003-3753-0489
Ekaterina PotapovaDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0003-4427-6335
Serena PernaDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0002-8892-3955
Maria Antonia BrighettiDepartment of Biology, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-4556-6468
Alessandro TravagliniDepartment of Biology, University of Rome Tor Vergata, Rome, Italy.ORCID 0000-0002-4373-0105
Pierluigi VerardoCenter of Aerobiology, Agenzia Regionale per la Protezione Ambientale, Pordenone, Italy.ORCID 0000-0002-8329-5160
Simone PelosiTPS Production, Rome, Italy.ORCID 0000-0002-6201-8068
Anna Maria ZicariDepartment of Pediatrics, Sapienza University of Rome, Rome, Italy.ORCID 0000-0002-2476-1790
Paolo Maria MatricardiDepartment of Pediatric Pulmonology, Immunology and Intensive Care Medicine, Charité University Medicine, Berlin, Germany.ORCID 0000-0001-5485-0324
Charité - Universitätsmedizin Berlin · DEOspedale Sandro Pertini · ITAzienda Ospedaliera Santa Maria Degli Angeli · ITUniversity of Rome Tor Vergata · ITAgenzia Regionale per la Protezione Ambientale del Piemonte · ITBambino Gesù Children's Hospital · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplete diagnosis and therapy of seasonal allergic rhinoconjunctivitis require evidence that exposure to the sensitizing pollen triggers allergic symptoms. Electronic clinical diaries, by recording disease severity scores and pollen exposure, can demonstrate this association. However, patients who spontaneously download an e-diary app show very low adherence to their recording.

objectiveThe objective of our study was to assess adherence of patients with seasonal allergic rhinitis to symptom recording via e-diary explicitly prescribed by an allergist within a blended care approach.

methodsThe @IT-2020 project is investigating the diagnostic synergy of mobile health and molecular allergology in patients with seasonal allergic rhinitis. In the pilot phase of the study, we recruited Italian children (Rome, Italy) and adults (Pordenone, Italy) with seasonal allergic rhinitis and instructed them to record their symptoms, medication intake, and general conditions daily through a mobile app (Allergy.Monitor) during the relevant pollen season.

resultsOverall, we recruited 101 Italian children (Rome) and 93 adults (Pordenone) with seasonal allergic rhinitis. Adherence to device use slowly declined during monitoring in 3 phases: phase A: first week, ≥1267/1358, 90%; phase B: second to sixth week, 4992/5884, 80% to 90%; and phase C: seventh week onward, 2063/2606, 70% to 80%. At the individual level, the adherence assessed in the second and third weeks of recording predicted with enough confidence (Rome: Spearman ρ=0.75; P<.001; Pordenone: ρ=0.81; P<.001) the overall patient adherence to recording and was inversely related to postponed reporting (ρ=-0.55; P<.001; in both centers). Recording adherence was significantly higher during the peak grass pollen season in Rome, but not in Pordenone.

conclusionsAdherence to daily recording in an e-diary, prescribed and motivated by an allergist in a blended care setting, was very high. This observation supports the use of e-diaries in addition to face-to-face visits for diagnosis and treatment of seasonal allergic rhinitis and deserves further investigation in real-life contexts.

Indexed as

AdolescentChildComplianceFemaleHumansMaleMobile ApplicationsRhinitis, Allergic, SeasonalTelemedicineblended caree-Diarymobile healthpollenprecision medicineseasonal allergic rhinitis

Identifiers

PMID32175909
PMCPMC7105930
OpenAlexW3011703392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.