Evidence map›Paper›PMID 32175842›Full record

ArticleeLife2020

Antagonistic regulation by insulin-like peptide and activin ensures the elaboration of appropriate dendritic field sizes of amacrine neurons.

Jiangnan Luo, Chun-Yuan Ting, Yan Li, Philip McQueen, Tzu-Yang Lin, Chao-Ping Hsu, Chi-Hon Lee

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Wdr59 promotes or inhibits TORC1 activity depending on cellular context.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  7. Article
  8. Article
  9. Neural specification, targeting, and circuit formation during visual system assembly.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  10. Article
  11. Extrinsic Factors Regulating Dendritic Patterning.Frontiers in cellular neuroscience · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jiangnan LuoSection on Neuronal Connectivity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States.
Chun-Yuan TingSection on Neuronal Connectivity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States.ORCID 0000-0002-2302-4203
Yan LiInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
Philip McQueenMathematical and Statistical Computing Laboratory, Center for Information Technology, National Institutes of Health, Bethesda, United States.
Tzu-Yang LinInstitute of Cellular and Organismic Biology, Academia Sinica, Taipei, Taiwan, Republic of China.
Chao-Ping HsuInstitute of Chemistry, Academia Sinica, Taipei, Taiwan, Republic of China.
Chi-Hon LeeSection on Neuronal Connectivity, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, United States.ORCID 0000-0002-6138-711X
National Institutes of Health · USInstitute of Cellular and Organismic Biology, Academia Sinica · TWNational Taiwan University · TW

Funding

Academia Sinica AS-IA-106-M01Ministry of Science and Technology, Taiwan 105-2113-M- 001-009- MY4NIH HHS HD008913
6 · The paper itself

Abstract

Establishing appropriate sizes and shapes of dendritic arbors is critical for proper wiring of the central nervous system. Here we report that Insulin-like Peptide 2 (DILP2) locally activates transiently expressed insulin receptors in the central dendrites of

Indexed as

ActivinsAnimalsDrosophilaDrosophila ProteinsFluorescent Antibody TechniqueGene Expression RegulationModels, BiologicalMutationNeuronsNeuropeptidesPTEN PhosphohydrolaseReceptor, InsulinSignal TransductionTOR Serine-Threonine KinasesActivinsDrosophila ProteinsILP2 protein, DrosophilaNeuropeptidesPTEN PhosphohydrolaseReceptor, InsulinTOR Serine-Threonine Kinasesdendritesdevelopmental biologyD. melanogasterDrosophila visual systeminsulin/TORsynaptic GRASP

Identifiers

PMID32175842
PMCPMC7075694
OpenAlexW3010860057

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.