SynthesisCancer medicine2020
Prostate cancer risk in patients with melanoma: A systematic review and meta-analysis.
Synthesis in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.
- Risk factors for prostate cancer: An umbrella review of prospective observational studies and mendelian randomization analyses.PLoS medicine · 2024Pooled it
- Prostate cancer risk in patients with melanoma: A systematic review and meta-analysis.Cancer medicine · 2020Pooled it
- Characteristics and overall survival in patients with T1 melanoma: A nationwide matched cohort study.International journal of cancer · 2026Article
- Associations between cutaneous melanoma and prostate cancer: A bidirectional 2-sample Mendelian randomization study.Medicine · 2025Article
- Common skin cancers and their association with other non-cutaneous primary malignancies: a review of the literature.Medical oncology (Northwood, London, England) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe risk of prostate cancer in melanoma patients has been frequently assessed. However, a comprehensive meta-analysis specifically examining this association is lacking. Our aim was to quantify the risk of prostate cancer in melanoma patients based on the available evidence.
methodsA systematic review of the existing literature was performed in PubMed, Scopus, and Cochrane databases by two authors independently. Studies reporting the effect size in the form of standardized incidence ratio (SIR) were used for quantitative analyses.
resultsOf 17 studies included in the review, a total of 15 studies with 282 592 male melanoma patients were used for the analysis. Random-effects meta-analysis found a 24% increased risk (SIR = 1.24, 95% confidence interval 1.18 to 1.30) of prostate cancer in melanoma patients compared to the general population, with a prediction interval of 1.05 to 1.45. The risk was consistently significant for various geographical regions and latitude. Heterogeneity was significant (I
conclusionThese results suggest that the incidence of prostate cancer is significantly higher in patients with melanoma compared to the general population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.