Evidence map›Paper›PMID 32175577›Full record

ReviewJournal of animal science2020

Satellite cells and their regulation in livestock.

Madison L Gonzalez, Nicolas I Busse, Christy M Waits, Sally E Johnson

Registry-linked trialOpen access · bronzeAbstract readReview
In one paragraph

Review in Journal of animal science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05879575 (Effects and Pathophysiology of Weight Training on Pregnancy-related Pelvic Girdle Pain), which is not on this map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05879575 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Effects and Pathophysiology of Weight Training on Pregnancy-related Pelvic Girdle Pain (PPGP)

TypeinterventionalSponsorNational Taiwan University Hospital Hsin-Chu BranchRan2023 to 2024Enrolled70ConditionsPelvic Girdle PainArmsweight training
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. New insights into the skeletal muscle circadian clock in ruminants.Journal of animal science and biotechnology · 2026
    Review
  3. Birth Season and Breed Effects on NewbornAnimals : an open access journal from MDPI · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Curcumin-activated Wnt5a pathway mediates CaJournal of cachexia, sarcopenia and muscle · 2024
    Article
  10. Article
  11. Effect ofFrontiers in veterinary science · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Madison L GonzalezDepartment of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA.
Nicolas I BusseDepartment of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA.
Christy M WaitsLacerta Therapeutics, Alachua, FL.
Sally E JohnsonDepartment of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg, VA.
Virginia Tech · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Satellite cells are the myogenic stem and progenitor population found in skeletal muscle. These cells typically reside in a quiescent state until called upon to support repair, regeneration, or muscle growth. The activities of satellite cells are orchestrated by systemic hormones, autocrine and paracrine growth factors, and the composition of the basal lamina of the muscle fiber. Several key intracellular signaling events are initiated in response to changes in the local environment causing exit from quiescence, proliferation, and differentiation. Signals emanating from Notch, wingless-type mouse mammary tumor virus integration site family members, and transforming growth factor-β proteins mediate the reversible exit from growth 0 phase while those initiated by members of the fibroblast growth factor and insulin-like growth factor families direct proliferation and differentiation. Many of these pathways impinge upon the myogenic regulatory factors (MRF), myogenic factor 5, myogenic differentiation factor D, myogenin and MRF4, and the lineage determinate, Paired box 7, to alter transcription and subsequent satellite cell decisions. In the recent past, insight into mouse transgenic models has led to a firm understanding of regulatory events that control satellite cell metabolism and myogenesis. Many of these niche-regulated functions offer subtle differences from their counterparts in livestock pointing to the existence of species-specific controls. The purpose of this review is to examine the mechanisms that mediate large animal satellite cell activity and their relationship to those present in rodents.

Indexed as

Muscle DevelopmentAnimalsCell DifferentiationLivestockMiceMuscle Fibers, SkeletalMuscle, SkeletalMyogenic Regulatory Factor 5Myogenic Regulatory FactorsMyogeninSatellite Cells, Skeletal MuscleSomatomedinsMyogenic Regulatory Factor 5Myogenic Regulatory FactorsMyogeninSomatomedinslivestockmyogenesispaired box 7satellite cellskeletal muscle

Identifiers

PMID32175577
PMCPMC7193651
OpenAlexW3010923084

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.