Evidence map›Paper›PMID 32175497›Full record

ArticleACS omega2020

Bioinspired Dual-Responsive Nanofluidic Diodes by Poly-l-lysine Modification.

Jun Li, Pengrong An, Chuanguang Qin, Chun-Lin Sun, Miao Sun, Zhenming Ji, Chending Wang, Guanghua Du, Jie Liu, Yanbo Xie

Abstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jun LiMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.
Pengrong AnMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.
Chuanguang QinMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.
Chun-Lin SunState Key Laboratory of Applied Organic Chemistry (SKLAOC), College of Chemistry and Chemical Engineering, Lanzhou University, No. 222, TianShui Road(south), LanZhou City, GanSu Province 730000, P. R. China.
Miao SunMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.
Zhenming JiMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.
Chending WangMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.
Guanghua DuInstitute of Modern Physics, Chinese Academy of Sciences, No. 509, Nanchang Road, Lanzhou City, Gansu Province 730000, P. R. China.
Jie LiuInstitute of Modern Physics, Chinese Academy of Sciences, No. 509, Nanchang Road, Lanzhou City, Gansu Province 730000, P. R. China.
Yanbo XieMOE Key Laboratory of Material Physics and Chemistry Under Extraordinary Conditions, Joint Lab of Nanofluidics and Interfaces (LONI), School of Natural and Applied Sciences, Northwestern Polytechnical University, No. 127, Youyi Road (West), Xi'an City, Shaanxi Province 710072, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A smart nanofluidic device attracts attention as it enables to control the physicochemical properties and transportation phenomena, by using stimuli-responsive materials. This work reports a bioinspired modification of a conical ion track-etched polyethylene terephthalate nanopore surface by coating a layer of poly-l-lysine (PLL), which is a commonly used coating in biotechnology to achieve a dual-responsive nanofluidic channel by pH or temperature. The rectification of ionic transportation can be reversed by assembling PLL because of the change of surface bonds from the carboxyl to amine group. The PLL-modified nanopore becomes nonconductive as an "OFF" state at pH 11.5 and at a temperature of 70 °C in solution. The ionic transport in nanopores can be switched to the "ON" (conductive) state, by either decreasing pH or temperature. The transitions between "ON" and "OFF" states present excellent reversibility, which make the PLL-modified nanopores a promising smart nanofluidic device that can be used for drug delivery or biomimic ion/mass transport in future, besides the good biocompatibility and ease of use of PLL modification.

Identifiers

PMID32175497
PMCPMC7066557

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.