Evidence map›Paper›PMID 32175415›Full record

ArticleAnnals of translational medicine2020

External validation of the eighth edition of the TNM classification for lung cancer in 3,611 surgically treated patients at a single institution.

Jia Wang, Nan Wu, Chao Lv, Yue Yang

Abstract read
In one paragraph

Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Jia WangDepartment of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Nan WuDepartment of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Chao LvDepartment of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing 100142, China.
Yue YangDepartment of Thoracic Surgery II, Peking University Cancer Hospital & Institute, Beijing 100142, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA new revision of the tumor, node, metastasis (TNM) classification for lung cancer has been proposed by the International Association for the Study of Lung Cancer (IASLC), but external validation for it is required. This study aimed to evaluate stage groupings in the 8th edition of the TNM classification in an independent Chinese cohort.

methodsWe retrospectively analyzed 3,611 patients who were diagnosed as stage I to IV non-small cell lung cancer (NSCLC) and who received surgical treatment at our institute in China between October 2009 and August 2017. Long-rank tests were used to compare survival between two adjacent stage groups.

resultsBased on the 8th edition of the TNM classification, differences between every 2 adjacent stage groups were found to be significant except between Ia1 and Ia2 (P=0.062), and between IIIc and IVa (P=0.063). Significant differences were found between every 2 adjacent categories stratified by the T and N descriptors. Additionally, significant differences were found between M0 and M1a (P<0.001), while no significant difference was observed between M1a and M1b (P=0.092).

conclusionsOur study provides an external validation of the stage groupings in the 8th edition of the TNM staging system in surgically treated Chinese patients with NSCLC.

Indexed as

Chinese patientsneoplasm stagingnon-small cell lung cancer (NSCLC)tumor, node, metastasis classification (TNM classification)Validation study

Identifiers

PMID32175415
PMCPMC7049062

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