ArticleAnnals of translational medicine2020
Red blood cell distribution width is associated with mortality after acute ischemic stroke: a cohort study and systematic review.
Article in Annals of translational medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Red blood cell distribution width as a predictor of mortality and poor functional outcome after acute ischemic stroke: a meta-analysis and meta-regression.BMC neurology · 2024Pooled it
- Hepatorenal and Full Blood Count Profiles of Stroke Survivors Compared With Controls: A Case-Control Study.FASEB bioAdvances · 2026Article
- Association between red blood cell distribution width to albumin ratio and pneumonia risk in acute ischemic stroke: evidence from two independent cohorts.Frontiers in nutrition · 2026Article
- The link between red blood cell distribution width and 3-month prognosis in acute ischemic stroke patients: a secondary analysis of a cohort study.BMC neurology · 2025Article
- Clinical significance of the hemoglobin-to-red blood cell distribution width ratio in patients with severe OSAS.Scientific reports · 2025Article
- A Novel Nomogram Integrating Retinal Microvasculature and Clinical Indicators for Individualized Prediction of Early Neurological Deterioration in Single Subcortical Infarction.CNS neuroscience & therapeutics · 2025Observational
- Hemoglobin-to-Red Cell Distribution Width Ratio as a Predictor of Gastrointestinal Bleeding Following Percutaneous Coronary Intervention.Cardiology research and practice · 2025Article
- Assessing red blood cell distribution width in Vietnamese heart failure patients: A cross-sectional study.PloS one · 2024Article
- Article
- Association between red blood cell distribution width and the prognosis of brain death in patients with a Glasgow Coma Scale < 6.Scientific reports · 2023Article
- Association between red cell distribution width-to-platelet ratio and short-term and long-term mortality risk in patients with acute ischemic stroke.BMC neurology · 2023Article
- Higher serum homocysteine levels are associated with an increased risk of hemorrhagic transformation in patients with acute ischemic stroke.BMC neurology · 2023Article
- Propensity score analysis of red cell distribution width to serum calcium ratio in acute myocardial infarction as a predictor of in-hospital mortality.Frontiers in cardiovascular medicine · 2023Article
- Dose-Response Relationship between Red Blood Cell Distribution Width and In-Hospital Mortality in Oldest Old Patients with Acute Ischemic Stroke.Gerontology · 2023Article
- Red cell distribution width: a novel predictive biomarker for stroke risk after transient ischaemic attack.Annals of medicine · 2022Article
- Relationship between the Hemoglobin-to-Red Cell Distribution Width Ratio and All-Cause Mortality in Septic Patients with Atrial Fibrillation: Based on Propensity Score Matching Method.Journal of cardiovascular development and disease · 2022Article
- Laboratory prognostic factors for the long-term survival of multiple system atrophy.NPJ Parkinson's disease · 2022Article
- Article
- Postoperative red blood cell distribution width predicts functional outcome in aneurysmal subarachnoid hemorrhage after surgical clipping: A single-center retrospective study.Frontiers in neurology · 2022Article
- Acute Myocardial Infarction (AMI) as the Effect Modifiers to Modify the Association Between Red Blood Cell Distribution Width (RDW) and Mortality in Critically Ill Patients With Stroke.Frontiers in medicine · 2022Article
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Authors and funding
6 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether red blood cell distribution width (RDW) is associated with the prognosis of acute ischemic stroke is inconclusive according to recent studies. We performed a cohort study and meta-analysis to explore the association between RDW and functional outcome.
methodsPatients with ischemic stroke admitted to the Department of Neurology within 24 hours of stroke onset between January 1, 2015 to December 31, 2018 were enrolled. Blood was sampled within 24 hours after admission. We searched PubMed, Embase, Web of Science databases up to Nov 2019 to identify studies investigating the association between RDW values and prognosis following stroke. Outcomes included 3-month death and poor functional outcome [defined by modified Rankin Scale (mRS) score ≥3].
resultsWe included 1,558 patients in cohort study. RDW was independently associated with 3-month death [odds ratio (OR), 1.19; 95% confidence interval (CI), 1.03, 1.37], but not associated with 3-month poor outcome (OR 1.05, 95% CI, 0.95, 1.16), after adjustment for confounders. A dose-dependent relationship between RDW levels and 3-month death was revealed in the restricted cubic spline plot. Seven observational studies with 4,407 patients were identified for systematic review. When combining our study and previous studies, the association was significant for RDW predicting death (5 studies with 3,366 patients, OR 1.25, 95% CI, 1.15, 1.35), as well as for poor outcome (4 studies with 3,483 patients, OR 1.23, 95% CI, 1.05, 1.44).
conclusionsRDW was an independent predictor of 3-month functional outcome, and a trend of dose-dependent relationship between RDW and 3-month death was detected.
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