Evidence map›Paper›PMID 32175269›Full record

ArticleFrontiers in oncology2020

miR-15b-5p Promotes Growth and Metastasis in Breast Cancer by Targeting HPSE2.

Balu Wu, Guohong Liu, Yanxia Jin, Tian Yang, Dongdong Zhang, Lu Ding, Fuling Zhou, Yunbao Pan, Yongchang Wei

Abstract read
In one paragraph

Article in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  5. Application of serum miRNA panel in bladder cancer detection.Translational andrology and urology · 2026
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  7. Article
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  11. Review
  12. miRNAs in Signal Transduction of SMAD Proteins in Breast Cancer.International journal of molecular sciences · 2024
    Article
  13. Article
  14. Article
  15. Journal of Cancer · 2024
    Article
  16. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Balu WuDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Guohong LiuDepartment of Radiology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Yanxia JinDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Tian YangDepartment of Clinical Oncology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Dongdong ZhangDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Lu DingDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Fuling ZhouDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Yunbao PanDepartment of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.
Yongchang WeiHubei Key Laboratory of Tumor Biological Behaviors, Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MicroRNAs (miRNAs) can participate in many behaviors of various tumors. Prior studies have reported that miR-15b-5p in different tumors can either promote or inhibit tumor progression. In breast cancer, the role of miR-15b-5p is unclear. The main objective of this paper is to explore miR-15b-5p effects and their mechanisms in breast cancer using both

Indexed as

biomarkerbreast cancerHPSE2microRNAmiR-15b-5p

Identifiers

PMID32175269
PMCPMC7054484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.