Evidence map›Paper›PMID 32175010›Full record

ArticleBiotechnology for biofuels2020

Understanding the structural characteristics of water-soluble phenolic compounds from four pretreatments of corn stover and their inhibitory effects on enzymatic hydrolysis and fermentation.

Xiangxue Chen, Rui Zhai, Ying Li, Xinchuan Yuan, Zhi-Hua Liu, Mingjie Jin

Open access · goldAbstract read
In one paragraph

Article in Biotechnology for biofuels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 64 citations in OpenAlex.

  1. Structural genome variation drives adaptation of the xylose-fermenting yeast Scheffersomyces stipitis to lignocellulosic hydrolysates.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xiangxue Chen *1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei Street, Xuanwu District, Nanjing, 210094 China.
Rui Zhai *1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei Street, Xuanwu District, Nanjing, 210094 China.
Ying Li1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei Street, Xuanwu District, Nanjing, 210094 China.
Xinchuan Yuan1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei Street, Xuanwu District, Nanjing, 210094 China.
Zhi-Hua Liu2Department of Plant Pathology and Microbiology, College of Agriculture and Life Sciences, Texas A&M University, College Station, TX 77843 USA.
Mingjie Jin1School of Environmental and Biological Engineering, Nanjing University of Science and Technology, 200 Xiaolingwei Street, Xuanwu District, Nanjing, 210094 China.ORCID 0000-0002-9493-305X
Nanjing University of Science and Technology · CNTexas College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor bioethanol production from lignocellulosic biomass, phenolics derived from pretreatment have been generally considered as highly inhibitory towards enzymatic hydrolysis and fermentation. As phenolics are produced from lignin degradation during pretreatment, it is likely that the pretreatment will exert a strong impact on the structure of phenolics, resulting in varied levels of inhibition of the bioconversion process. Despite the extensive studies on pretreatment, it remains unclear how pretreatment process affects the properties of generated phenolics and how the inhibitory effect of phenolics from different pretreatment varies on enzymatic hydrolysis and fermentation.

resultsIn this study, the structural properties of phenolic compounds derived from four typical pretreatment [dilute acid (DA), liquid hot water pretreatment (LHW), ammonia fiber expansion (AFEX) and alkaline pretreatment (AL)] were characterized, and their effect on both enzymatic hydrolysis and fermentation were evaluated. The inhibitory effect of phenolics on enzymatic hydrolysis followed the order: AFEX > LHW > DA > AL, while the inhibitory effect of phenolics on

conclusionsPretreatment process greatly affects the properties of generated phenolics and the inhibitory effects of phenolics on enzymatic hydrolysis and fermentation. This study provides new insight for further pretreatment modification and hydrolysate detoxification to minimize phenolics-caused inhibition and enhance the efficiency of enzymatic hydrolysis and fermentation.

Indexed as

Enzymatic hydrolysisFermentationLignocellulosic biomassPhenolic inhibitionPretreatment

Identifiers

PMID32175010
PMCPMC7065323
OpenAlexW3012150406

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.