Evidence map›Paper›PMID 32175007›Full record

ArticleBiotechnology for biofuels2020

Metabolic and evolutionary responses of

Evert K Holwerda, Daniel G Olson, Natalie M Ruppertsberger, David M Stevenson, Sean J L Murphy, Marybeth I Maloney, Anthony A Lanahan, Daniel Amador-Noguez, Lee R Lynd

Abstract read
In one paragraph

Article in Biotechnology for biofuels, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. EngineeringMetabolic engineering communications · 2026
    Article
  5. EngineeringbioRxiv : the preprint server for biology · 2025
    Article
  6. Identification of electron transfer enzymes inJournal of bacteriology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The potential of native and engineered Clostridia for biomass biorefining.Frontiers in bioengineering and biotechnology · 2024
    Review
  12. Ethanol tolerance in engineered strains of Clostridium thermocellum.Biotechnology for biofuels and bioproducts · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Characterization ofBiology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Evert K Holwerda *1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.ORCID 0000-0002-0565-392X
Daniel G Olson *1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.
Natalie M Ruppertsberger1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.
David M Stevenson2Department of Bacteriology, University of Wisconsin, Madison, WI 53706 USA.
Sean J L Murphy1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.
Marybeth I Maloney1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.
Anthony A Lanahan1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.
Daniel Amador-Noguez2Department of Bacteriology, University of Wisconsin, Madison, WI 53706 USA.
Lee R Lynd1Thayer School of Engineering, Dartmouth College, Hanover, NH 03755 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEngineering efforts targeted at increasing ethanol by modifying the central fermentative metabolism of

resultsContrary to lactate dehydrogenase, deleting phosphotransacetylase (

conclusionsModifications in the organic acid fermentative pathways in

Indexed as

Adaptive laboratory evolutionadhEAmino acid secretionCellulose utilizationChemostat cultivationClostridium thermocellumEthanolhfsBIsobutanol

Identifiers

PMID32175007
PMCPMC7063780

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.