Evidence map›Paper›PMID 32174902›Full record

ArticleFrontiers in microbiology2020

Leucine-Rich Immune Factor APL1 Is Associated With Specific Modulation of Enteric Microbiome Taxa in the Asian Malaria Mosquito

Christian Mitri, Emmanuel Bischoff, Eugeni Belda Cuesta, Stevenn Volant, Amine Ghozlane, Karin Eiglmeier, Inge Holm, Constentin Dieme, Emma Brito-Fravallo, Wamdaogo M Guelbeogo and 3 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. mBio · 2026
    Article
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  3. Article
  4. Article
  5. Review
  6. Recovery of metagenomic data from theWellcome open research · 2023
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Christian MitriUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Emmanuel BischoffUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Eugeni Belda CuestaIntegromics Unit, Institute of Cardiometabolism and Nutrition, Assistance Publique Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France.
Stevenn VolantBioinformatics and Biostatistics Hub, Department of Computational Biology, Institut Pasteur, Paris, France.
Amine GhozlaneBioinformatics and Biostatistics Hub, Department of Computational Biology, Institut Pasteur, Paris, France.
Karin EiglmeierUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Inge HolmUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Constentin DiemeUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Emma Brito-FravalloUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.
Wamdaogo M GuelbeogoCentre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso.
N'Fale SagnonCentre National de Recherche et de Formation sur le Paludisme, Ouagadougou, Burkina Faso.
Michelle M RiehleDepartment of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, United States.
Kenneth D VernickUnit of Insect Vector Genetics and Genomics, Department of Parasites and Insect Vectors, Institut Pasteur, Paris, France.

Funding

Noncoding DNA regulatory elements and Anopheles vector biologyR01AI145999 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI RIEHLE, MICHELLE M · 2020 to 2024
$1.8M
Gene enhancer mapping technology in AnophelesR21AI121587 · NIAID · UNIVERSITY OF MINNESOTA · PI RIEHLE, MICHELLE M · 2016 to 2017
$421k
NIAID NIH HHS R01 AI145999NIAID NIH HHS R21 AI121587
6 · The paper itself

Abstract

The commensal gut microbiome is contained by the enteric epithelial barrier, but little is known about the degree of specificity of host immune barrier interactions for particular bacterial taxa. Here, we show that depletion of leucine-rich repeat immune factor APL1 in the Asian malaria mosquito

Indexed as

commensalisminsect immunityleucine-rich repeatmicrobiomemosquito

Identifiers

PMID32174902
PMCPMC7054466

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.