Evidence map›Paper›PMID 32174728›Full record

ArticleJournal of parasitic diseases : official organ of the Indian Society for Parasitology2020

Interaction of apigenin-7-O-glucoside with pyrimethamine against

Daniel A Abugri, William H Witola

Open access · bronzeAbstract read
In one paragraph

Article in Journal of parasitic diseases : official organ of the Indian Society for Parasitology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Phytochemical profiling andFrontiers in chemistry · 2024
    Article
  2. Article
  3. Article
  4. Article
  5. Antimicrobial, Antivirulence, and Antiparasitic Potential ofAntibiotics (Basel, Switzerland) · 2022
    Article
  6. Parasitology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Daniel A Abugri1Department of Chemistry, Laboratory of Ethnomedicine, Parasitology and Drug Discovery, Tuskegee University, Tuskegee, AL 36088 USA.
William H Witola3Department of Pathobiology, College of Veterinary Medicine, University of Illinois, 2432 VMBSB, MC-002, 2001 South Lincoln Avenue, Urbana, Champaign, IL USA.
Tuskegee University · USUniversity of Illinois Urbana-Champaign · US

Funding

INFRASTRUCTURE IIG12MD007585 · NIMHD · TUSKEGEE UNIVERSITY · PI YATES, CLAYTON · 2012 to 2016
$4.6M
NIMHD NIH HHS G12 MD007585
6 · The paper itself

Abstract

Apigenin-7-O-glucoside, a flavonoid glucoside known to inhibit cancer cell growth, fungi growth, both intra and extracellular reactive oxygen species generation, causing cell arrest and damage to the plasma membrane, was tested alone or in combination with a dihydrofolate inhibitor (pyrimethamine) against

Indexed as

Anti-toxoplasmosisDrug combinationFlavonoid glucosidePyrimethamine

Identifiers

PMID32174728
PMCPMC7046874
OpenAlexW2991673147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.