ArticleIndian journal of ophthalmology2020
Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy: One-year study.
Article in Indian journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Efficacy and safety of intraoperative injection of mitomycin C during trabeculectomy: a systematic review and meta-analysis.International ophthalmology · 2024Pooled it
- Long-term outcomes of Mitomycin-C augmented trabeculectomy using subconjunctival injections versus soaked sponges: a randomised controlled trial.Eye (London, England) · 2024Trial
- Short-term outcomes of Mitomycin-C augmented phaco-trabeculectomy using subconjunctival injections versus soaked sponges: a randomized controlled trial.Eye (London, England) · 2024Trial
- Comparative evaluation of outcomes of novel approach of subconjunctival Mitomycin C (MMC) injection at the end of trabeculectomy versus intraTenon injection of MMC prior to the initial conjunctival incision - A pilot study.Indian journal of ophthalmology · 2022Trial
- Three-year outcomes of two-stage intra-Tenon low-dose mitomycin C injection versus sponge application in trabeculectomy.BMJ open ophthalmology · 2025Article
- Hidden complication: retained cellulose sponge following trabeculectomy with subconjunctival mitomycin C.International ophthalmology · 2025Article
- Safety and efficacy of a unique scleral flap in mitomycin C-augmented trabeculectomy over one year.Scientific reports · 2025Article
- Efficacy and Safety of the Subtenon Injection of 0.01% Mitomycin C-augmented Trabeculectomy.Cureus · 2024Article
- Two-stage intra-tenon injection versus sponge-applied mitomycin C-augmented trabeculectomy: a one-year study.International ophthalmology · 2023Article
- Augmented trabeculectomy - The surgical journey and road trip forward.Indian journal of ophthalmology · 2023Article
- Subconjunctival filtration in evolution: current evidence on MicroShunt implantation for treating patients with glaucoma.Eye and vision (London, England) · 2023Review
- National survey of intraoperative mitomycin C use during trabeculectomy surgery in the UK.International ophthalmology · 2021Article
- Comments on: Intraoperative injection versus sponge-applied mitomycin C during trabeculectomy: One-year study.Indian journal of ophthalmology · 2021Article
- Response to comments on: Intraoperative injection versus sponge-applied Mitomycin C during trabeculectomy: One-year study.Indian journal of ophthalmology · 2021Article
- Reply to comments on: Intraoperative injection versus sponge-Applied mitomycin C during trabeculectomy: One - year study.Indian journal of ophthalmology · 2021Article
- Comments on: Intraoperative injection versus sponge applied mitomycin C during trabeculectomy: One year study.Indian journal of ophthalmology · 2021Article
- Delayed Onset Scleromalacia and Conjunctival Bleb Formation Following Intraoperative Mitomycin C Application during Conjunctival Melanoma Excision.Vision (Basel, Switzerland) · 2020Article
- Safety and Efficacy of Mitomycin C: Augmented Trabeculectomy: Subtenon's Injection versus Sponge Application.International journal of applied & basic medical researchArticle
- Sponge Application of Mitomycin C vs Sub-Tenon Injection in Trabeculectomy: A Randomized Controlled Trial.Journal of current glaucoma practiceArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: To determine the safety and efficacy of mitomycin C (MMC) injection versus sponge during trabeculectomy. Methods: It is a prospective analysis of patients who underwent trabeculectomy with MMC and followed up for 1 year, divided into two groups, namely, group 1- injection (n = 21), group 2-> sponge (n = 21). The same concentration of MMC was used for both groups. Inclusion criteria were trabeculectomies with MMC for intraocular pressure (IOP) control in eyes with glaucoma (primary + secondary) with a follow-up of 1 year. Results: Mean preoperative IOP in group 1 was 29.00 ± 11.92 mmHg and group 2 was 25.87 ± 11.09 mmHg, which reduced to 12.19 ± 4.03 and 15.56 ± 10.72 mmHg at final visit with P value of 0.0002 and 0.001, respectively. Mean preoperative number of antiglaucoma medications was 2.4 ± 0.87 in group 1 and 2.3 ± 0.96 in group 2, which reduced to 0.38 ± 0.5 and 0.91 ± 0.85 with P value of 0.001 and 0.0003, respectively. The complete success rate was 52.4% in the injection group and 26.1% in the sponge group at end of 1 year. Overall, success rate (complete + qualified) was 90.5% and 87% in group 1 and group 2 at final visit. All major complications were encountered in sponge group. 1 (11.1%) patient developed choroidal detachment and one had malignant glaucoma which got resolved by medical management. 33.3% cases had encapsulated bleb which received bleb needling. 44.4% cases underwent Argon laser suture lysis postoperatively. Conclusion: The MMC injection may be as safe and as effective as conventional sponge application with comparable estimated complete treatment success.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.