Evidence map›Paper›PMID 32174140›Full record

ArticleAmerican journal of physiology. Renal physiology2020

Ubiquitination of renal ENaC subunits in vivo.

Gustavo Frindt, Marko Bertog, Christoph Korbmacher, Lawrence G Palmer

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 22 citations in OpenAlex.

  1. ENaC processing in rat kidney: effects of salt loading and ADH.American journal of physiology. Renal physiology · 2026
    Article
  2. Article
  3. Article
  4. Control of ENaC ubiquitination.American journal of physiology. Renal physiology · 2024
    Article
  5. The Epithelial Sodium Channel-An Underestimated Drug Target.International journal of molecular sciences · 2023
    Review
  6. Differentiated mouse kidney tubuloids as a novelFrontiers in cell and developmental biology · 2023
    Article
  7. Expression of ENaC subunits in epithelia.The Journal of general physiology · 2022
    Article
  8. Review
  9. Elevated intracellular NaProceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Article
  11. Optogenetic Control of PIP2 Interactions Shaping ENaC Activity.International journal of molecular sciences · 2022
    Article
  12. Review
  13. Epithelial Sodium Channel and Salt-Sensitive Hypertension.Hypertension (Dallas, Tex. : 1979) · 2021
    Review
  14. Cleavage state of γENaC in mouse and rat kidneys.American journal of physiology. Renal physiology · 2021
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Gustavo FrindtDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Marko BertogInstitut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Christoph KorbmacherInstitut für Zelluläre und Molekulare Physiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Lawrence G PalmerDepartment of Physiology and Biophysics, Weill-Cornell Medical College, New York, New York.
Cornell University · USFriedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Regulation of ENaC Trafficking and Activity in the KidneyR01DK111380 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI PALMER, LAWRENCE G · 2017 to 2025
$3.1M
NIDDK NIH HHS R01 DK111380
6 · The paper itself

Abstract

Ubiquitination of the epithelial Na

Indexed as

UbiquitinationAldosteroneAnimalsDisease Models, AnimalEpithelial Sodium ChannelsFemaleKidneyLiddle SyndromeMaleMice, Inbred C57BLMice, Mutant StrainsMutationProteolysisRats, Sprague-DawleyAldosteroneEpithelial Sodium ChannelsScnn1b protein, mouseepithelial Na+ channelLiddle syndromemiceproteolysisrats

Identifiers

PMID32174140
PMCPMC7294337
OpenAlexW3011687801

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.