Evidence map›Paper›PMID 32174139›Full record

ArticleAmerican journal of physiology. Renal physiology2020

High-fructose corn syrup-sweetened soft drink consumption increases vascular resistance in the kidneys at rest and during sympathetic activation.

Christopher L Chapman, Tigran Grigoryan, Nicole T Vargas, Emma L Reed, Paul J Kueck, Leonard D Pietrafesa, Adam C Bloomfield, Blair D Johnson, Zachary J Schlader

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Renal physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Hydrating with a higher-fructose sport drink does not worsen acute kidney injury risk during simulated work-related heat stress.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Trial
  2. Sugar-sweetened soft drink consumption acutely decreases spontaneous baroreflex sensitivity and heart rate variability.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Trial
  3. Trial
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  11. An American Physiological Society cross-journal Call for Papers on "The Physiology of Obesity".American journal of physiology. Lung cellular and molecular physiology · 2022
    Article
  12. Review
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  16. Occupational heat exposure and the risk of chronic kidney disease of nontraditional origin in the United States.American journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Christopher L ChapmanCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.ORCID 0000-0001-9717-4776
Tigran GrigoryanCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Nicole T VargasCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Emma L ReedCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Paul J KueckCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Leonard D PietrafesaCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Adam C BloomfieldCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.
Blair D JohnsonCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.ORCID 0000-0002-1731-4415
Zachary J SchladerCenter for Research and Education in Special Environments, Department of Exercise and Nutrition Sciences, University at Buffalo, Buffalo, New York.ORCID 0000-0003-3590-3958
University at Buffalo, State University of New York · USIndiana University Bloomington · US

Funding

Occupational Safety and Health Research (R01)R01OH011528 · OH · TRUSTEES OF INDIANA UNIVERSITY · PI SCHLADER, ZACHARY JOSEPH · 2019 to 2022
$2.2M
NIOSH CDC HHS R01 OH011528
6 · The paper itself

Abstract

We first tested the hypothesis that consuming a high-fructose corn syrup (HFCS)-sweetened soft drink augments kidney vasoconstriction to sympathetic stimulation compared with water (

Indexed as

Artificially Sweetened BeveragesBlood Flow VelocityCaffeineFemaleHealthy VolunteersHigh Fructose Corn SyrupHumansKidneyMaleRandom AllocationRenal ArteryRenal CirculationSympathetic Nervous SystemTime FactorsUp-RegulationUric AcidCaffeineHigh Fructose Corn SyrupUric AcidVasopressinsDoppler ultrasoundrenal blood velocityrenal vascular resistancesodauric acidvasopressin

Identifiers

PMID32174139
PMCPMC7191446
OpenAlexW3011915617

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.