ArticleJournal of Korean medical science2020
Associations of Plasma Neutrophil Gelatinase-associated Lipocalin, Anemia, and Renal Scarring in Children with Febrile Urinary Tract Infections.
Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- The value of procalcitonin and urinary NGAL in the prediction of acute pyelonephritis and kidney scarring in pediatric patients with a history of febrile urinary tract infection: a systematic review and meta-analysis.Pediatric nephrology (Berlin, Germany) · 2026Pooled it
- A Multimodal Fuzzy Approach in Evaluating Pediatric Chronic Kidney Disease Using Kidney Biomarkers.Diagnostics (Basel, Switzerland) · 2024Article
- Analysis of relevant influencing factors for recurrent urinary tract infections in children: exploring predictive factors and intervention measures.American journal of translational research · 2024Article
- Urine specific gravity, pyuria, and neutrophil gelatinase-associated lipocalin for identifying urinary tract infection in young children.Pediatric nephrology (Berlin, Germany) · 2023Article
- Lipocalin-2, Soluble Transferrin Receptor, and Erythropoietin in Anemia During Mild Renal Dysfunction.International journal of general medicine · 2023Article
- MR-Proadrenomedullin as biomarker of renal damage in urinary tract infection in children.BMC pediatrics · 2021Article
- Serum neutrophil gelatinase-associated lipocalin for predicting anemia of inflammation in children with urinary tract infection.Central-European journal of immunology · 2021Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeutrophil gelatinase-associated lipocalin (NGAL), a bacteriostatic agent, is known to inhibit erythropoiesis leading to anemia. We aimed to investigate the associations of NGAL, anemia, and renal scarring in children with febrile urinary tract infections (UTIs).
methodsWe retrospectively reviewed the medical records of 261 children with febrile UTIs. The relationship between the presence of anemia and plasma NGAL levels was investigated. NGAL performance in comparison with serum C-reactive protein (CRP) at admission and after 72 hours of treatment was also evaluated for the prediction of renal scarring as well as acute pyelonephritis (APN) and vesicoureteral reflux (VUR).
resultsPlasma NGAL levels were elevated in patients with anemia compared with those without anemia. Multiple linear regression analysis showed an inverse relationship between NGAL levels and erythrocyte counts (standard β = -0.397,
conclusionIncreased plasma NGAL levels may be associated with the presence of anemia and renal scarring in children with febrile UTIs.
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