Evidence map›Paper›PMID 32174053›Full record

ArticleKorean journal of radiology2020

False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases.

Dasheng Li, Dawei Wang, Jianping Dong, Nana Wang, He Huang, Haiwang Xu, Chen Xia

Registry-linked trialAbstract readCase Reports
In one paragraph

Article in Korean journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04479319 (Developing Hybrid Decision Support System Algorithm for COVID-19 Diagnosis Between RT-PCR Graphics and Thorax CT Images Using Deep Learning), which is not on this map. Cited by 209 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
209citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04479319 completednot on this map

Developing Hybrid Decision Support System Algorithm for COVID-19 Diagnosis Between RT-PCR Graphics and Thorax CT Images Using Deep Learning

TypeobservationalSponsorAnkara UniversityRan2020 to 2022Enrolled3,215ConditionsCovid19ArmsThorax CT
3 · Its place in the literature

Who cites it

209 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  11. Recommendations from the CSO-HNS taskforce on performance of tracheotomy during the COVID-19 pandemic.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2020
    Guideline
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149 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Dasheng LiDepartment of Radiology, Beijing Haidian Section of Peking University Third Hospital (Beijing Haidian Hospital), Beijing, China. 724501143@qq.com.ORCID 0000-0002-5071-5739
Dawei WangInstitute of Advanced Research, Infervision, Beijing, China.ORCID 0000-0002-8670-1961
Jianping DongDepartment of Infection, Beijing Haidian Section of Peking University Third Hospital (Beijing Haidian Hospital), Beijing, China.
Nana WangDepartment of Radiology, Beijing Haidian Section of Peking University Third Hospital (Beijing Haidian Hospital), Beijing, China.
He HuangDepartment of Radiology, Beijing Haidian Section of Peking University Third Hospital (Beijing Haidian Hospital), Beijing, China.
Haiwang XuDepartment of Radiology, Beijing Haidian Section of Peking University Third Hospital (Beijing Haidian Hospital), Beijing, China.
Chen XiaInstitute of Advanced Research, Infervision, Beijing, China.ORCID 0000-0002-8839-0220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.

Indexed as

Reverse Transcriptase Polymerase Chain ReactionAdultBetacoronavirusClinical Laboratory TechniquesCoronavirus InfectionsCOVID-19COVID-19 TestingCOVID-19 VaccinesDeep LearningFalse Negative ReactionsHumansInfantMalePneumonia, ViralSARS-CoV-2Tomography, X-Ray ComputedCovid-19 aAPC vaccineCOVID-19 VaccinesComputed tomographyCOVID-19False-negative resultsLaboratory examinationrRT-PCRSARS-COV-2

Identifiers

PMID32174053
PMCPMC7082661

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.