ArticleTransboundary and emerging diseases2020
First detection of Theileria parva in cattle from Cameroon in the absence of the main tick vector Rhipicephalus appendiculatus.
Article in Transboundary and emerging diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Tick-Borne Diseases in Sub-Saharan Africa: A Systematic Review of Pathogens, Research Focus, and Implications for Public Health.Pathogens (Basel, Switzerland) · 2024Pooled it
- Global distribution, pathogen spectrum, and invasion potential ofOne health (Amsterdam, Netherlands) · 2026Article
- Molecular Prevalence and Genetic Characterization of Bovine Tick-Borne Protozoa in Thai and Imported Beef Cattle in Thai-Myanmar Border and Infesting Ticks from Kanchanaburi Province, Thailand.Pathogens (Basel, Switzerland) · 2026Article
- Epidemiological, haematological-biochemical, and molecular investigations of bovine theileriosis with therapeutic evaluation of buparvaquone with silymarin in Dakahlia and Damietta governorates, Egypt.Veterinary research communications · 2026Article
- Morbidity, mortality, and risk factors associated withVeterinary and animal science · 2025Article
- Ticks (Acari: Ixodidae) and tick-borne diseases in Cameroon: Current understanding and future directions for more comprehensive surveillance.One health (Amsterdam, Netherlands) · 2025Review
- Distribution and Prevalence of Ticks and Tick-Borne Pathogens at the Wildlife-Livestock Interface in Africa: A Systematic Review.Veterinary sciences · 2025Review
- Beyond the jab: Unravelling the complexities of vaccine adoption for East Coast Fever in rural Kenya.PloS one · 2025Article
- Seroprevalence and risk factors associated withVeterinary world · 2024Article
- Conservation and variation in the region of the Theileria parva p104 antigen coding gene used for PCR surveillance of the parasite.Parasitology research · 2023Article
- Detection of Tick-Borne Pathogens in Ticks from Cattle in Western Highlands of Cameroon.Microorganisms · 2022Article
- Recent Progress on Tick-Borne Animal Diseases of Veterinary and Public Health Significance in China.Viruses · 2022Review
- Characterization of a Novel ChimericVaccines · 2022Article
- Isolation of infectious Theileria parva sporozoites secreted by infected Rhipicephalus appendiculatus ticks into an in vitro tick feeding system.Parasites & vectors · 2021Article
- Genetic Diversity and Sequence Polymorphism of Two Genes Encoding Theileria parva Antigens Recognized by CD8Pathogens (Basel, Switzerland) · 2020Article
- First detection of Theileria parva in cattle from Cameroon in the absence of the main tick vector Rhipicephalus appendiculatus.Transboundary and emerging diseases · 2020Article
Corrections and comments
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Authors and funding
14 authors at 6 institutions in 4 countries.
Funding
Abstract
A major risk factor for the spread of livestock diseases and their vectors is the uncontrolled transboundary movement of live animals for trade and grazing. Such movements constrain effective control of tick-transmitted pathogens, including Theileria parva. Only limited studies have been undertaken to identify ticks and tick-borne diseases (TTBDs) affecting cattle in central African countries, including Cameroon. We hereby report the collection of baseline data on the prevalence of T. parva in Cameroon through a countrywide cross-sectional survey, conducted in 2016, involving collection of blood samples from cattle from 63 sites across the five agro-ecological zones (AEZs) of the country. ELISA-based surveillance of infected cattle was performed on 479 randomly selected samples and revealed specific antibodies to T. parva in 22.7% and T. mutans in 41.1% of cattle. Screening of 1,340 representative DNA samples for the presence of T. parva identified 25 (1.86%) positives using a p104 antigen gene-based nested PCR assay. The positives were distributed across agro-ecological zones I, II, III and V. None of the p104 positive cattle exhibited clinical symptoms of East Coast fever (ECF). Using reverse line blot (RLB), 58 (4.3%) and 1,139 (85%) of the samples reacted with the T. parva and T. mutans oligonucleotide probes, respectively. This represents the first report of T. parva from Cameroon. Surprisingly, no Rhipicephalus appendiculatus ticks, the main vector of T. parva, were identified in a parallel study involving comprehensive morphological and molecular survey of tick species present in the country. Only two of the 25 p104 positive cattle were PCR-positive for the CD8+ T-cell target schizont-expressed antigen gene Tp1. Cloning and sequencing of Tp1 amplicons revealed sequence identity with the reference T. parva Muguga. This new finding raises serious concerns of a potential spread of ECF into the central African region.
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Registered trials
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