Evidence map›Paper›PMID 32173857›Full record

ReviewImmunology2020

The developing immune network in human prenatal skin.

Rachel Anne Botting, Muzlifah Haniffa

Open access · hybridAbstract readReview
In one paragraph

Review in Immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Prenatal PMNature communications · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. The Immune Functions of Keratinocytes in Skin Wound Healing.International journal of molecular sciences · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Rachel Anne BottingFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0001-9595-4605
Muzlifah HaniffaFaculty of Medical Sciences, Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK.
Newcastle University · GBWellcome Sanger Institute · GB

Funding

Wellcome Trust WT107931/Z/15/Z
6 · The paper itself

Abstract

Establishment of a well-functioning immune network in skin is crucial for its barrier function. This begins in utero alongside the structural differentiation and maturation of skin, and continues to expand and diversify across the human lifespan. The microenvironment of the developing human skin supports immune cell differentiation and has an overall anti-inflammatory profile. Immunologically inert and skewed immune populations found in developing human skin promote wound healing, and as such may play a crucial role in the structural changes occurring during skin development.

Indexed as

Immunity, CellularAntigen-Presenting CellsCell DifferentiationEmbryonic DevelopmentErythrocytesHumansImmune ToleranceLymphocytesMast CellsSkinWound Healinghaematopoiesisimmune homeostasisregulation/suppressionskin

Identifiers

PMID32173857
PMCPMC7218404
OpenAlexW3011449067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.