Evidence map›Paper›PMID 32173681›Full record

ReviewFukushima journal of medical science2020

Autoantibodies associated with neuropsychiatric systemic lupus erythematosus: the quest for symptom-specific biomarkers.

Shuzo Sato, Jumpei Temmoku, Yuya Fujita, Makiko Yashiro-Furuya, Naoki Matsuoka, Tomoyuki Asano, Hiroko Kobayashi, Hiroshi Watanabe, Kiyoshi Migita

Open access · diamondAbstract readReview
In one paragraph

Review in Fukushima journal of medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
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  8. Cellular therapies in rheumatic and musculoskeletal diseases.Journal of translational autoimmunity · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shuzo SatoDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Jumpei TemmokuDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Yuya FujitaDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Makiko Yashiro-FuruyaDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Naoki MatsuokaDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Tomoyuki AsanoDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Hiroko KobayashiDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Hiroshi WatanabeDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Kiyoshi MigitaDepartment of Rheumatology, Fukushima Medical University School of Medicine.
Fukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that affects multiple organs, including the central nervous system. Neuropsychiatric SLE (NPSLE) is a severe and potentially fatal condition. Several factors including autoantibodies have been implicated in the pathogenesis of NPSLE. However, definitive biomarkers of NPSLE are yet to be identified owing to the complexity of this disease. This is a major barrier to accurate and timely diagnosis of NPSLE. Studies have identified several autoantibodies associated with NPSLE;some of these autoantibodies are well investigated and regarded as symptom-specific. In this review, we discuss recent advances in our understanding of the manifestations and pathogenesis of NPSLE. In addition, we describe representative symptom-specific autoantibodies that are considered to be closely associated with the pathogenesis of NPSLE.

Indexed as

Antibodies, AntiphospholipidAutoantibodiesBiomarkersGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)HumansLupus Vasculitis, Central Nervous SystemReceptors, N-Methyl-D-AspartateRibosomal ProteinsTriose-Phosphate IsomeraseAntibodies, AntiphospholipidAutoantibodiesBiomarkersGAPDH protein, humanGlyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating)Receptors, N-Methyl-D-AspartateRibosomal ProteinsTriose-Phosphate Isomeraseautoantibodybiomarkerneuropsychiatric systemic lupus erythematosuspathogenesissymptom-specific

Identifiers

PMID32173681
PMCPMC7269884
OpenAlexW3011730693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.