Evidence map›Paper›PMID 32173345›Full record

ArticleRedox biology2020

Neurogranin regulates eNOS function and endothelial activation.

Vino T Cheriyan, Mabruka Alfaidi, Ashton N Jorgensen, Md Ashiqul Alam, Chowdhury S Abdullah, Gopi K Kolluru, Md Shenuarin Bhuiyan, Christopher G Kevil, A Wayne Orr, Hyung W Nam

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  7. S100 proteins in cardiovascular diseases.Molecular medicine (Cambridge, Mass.) · 2023
    Review
  8. Article
  9. Neurogranin regulates calcium-dependent cardiac hypertrophy.Experimental and molecular pathology · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Vino T CheriyanDepartment of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Mabruka AlfaidiDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Ashton N JorgensenDepartment of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Md Ashiqul AlamDepartment of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Chowdhury S AbdullahDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Gopi K KolluruDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Md Shenuarin BhuiyanDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Christopher G KevilDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
A Wayne OrrDepartment of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA.
Hyung W NamDepartment of Pharmacology, Toxicology, and Neuroscience, Louisiana State University Health Sciences Center, Shreveport, LA, 71130, USA. Electronic address: hnam@lsuhsc.edu.
Louisiana State University Health Sciences Center Shreveport · US

Funding

Stress Exacerbates Myocardial Ischemic Injury by Blocking Estrogen's Antidoxidant Protection in the Female HeartP20GM121307 · NIGMS · LOUISIANA STATE UNIV HSC SHREVEPORT · PI Christopher G Kevil · 2018 to 2026
$23.6M
Nck Adaptor Proteins in Atherogenic Endothelial ActivationR01HL133497 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2016 to 2024
$3.8M
Matrix Signaling in Endothelial Cell DysfunctionR01HL098435 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2010 to 2020
$3.2M
Sigmar1 in lipid metabolismR01HL145753 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI BHUIYAN, MD. SHENUARIN · 2019 to 2023
$2.6M
EphA2 signaling in atherosclerotic fibroproliferative remodelingR01HL141155 · NHLBI · LOUISIANA STATE UNIV HSC SHREVEPORT · PI ORR, ANTHONY WAYNE · 2019 to 2022
$1.8M
NHLBI NIH HHS R01 HL098435NHLBI NIH HHS R01 HL133497NHLBI NIH HHS R01 HL141155NHLBI NIH HHS R01 HL145753NIGMS NIH HHS P20 GM121307
6 · The paper itself

Abstract

Endothelial nitric oxide (NO) is a critical mediator of vascular function and vascular remodeling. NO is produced by endothelial nitric oxide synthase (eNOS), which is activated by calcium (Ca

Indexed as

NeurograninNitric Oxide Synthase Type IIIAnimalsCells, CulturedEndothelial CellsMiceNitric OxidePhosphorylationNeurograninNitric OxideNitric Oxide Synthase Type IIINos3 protein, mouseEndothelial dysfunctionFlow-mediated dilationNeurograninNitric oxideOxidative stressShear stress

Identifiers

PMID32173345
PMCPMC7327963
OpenAlexW3011723837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.