Evidence map›Paper›PMID 32172808›Full record

ReviewCritical care clinics2020

Cell-Cell Communication Breakdown and Endothelial Dysfunction.

Daniel D Lee, Margaret A Schwarz

Open access · greenAbstract readReview
In one paragraph

Review in Critical care clinics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Daniel D LeeIndiana University School of Medicine, 1234 Notre Dame Avenue, South Bend, IN 46617, USA.
Margaret A SchwarzIndiana University School of Medicine, 1234 Notre Dame Avenue, South Bend, IN 46617, USA. Electronic address: schwarma@iu.edu.
Indiana University School of MedicineUniversity of Notre Dame · US

Funding

Decoding Mediators in Lung DevelopmentR21HD090227 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI SCHWARZ, MARGARET A · 2018 to 2019
$433k
NICHD NIH HHS R21 HD090227
6 · The paper itself

Abstract

Guided by organ-specific signals in both development and disease response, the heterogeneous endothelial cell population is a dynamic member of the vasculature. Functioning as the gatekeeper to fluid, inflammatory cells, oxygen, and nutrients, endothelial cell communication with its local environment is critical. Impairment of endothelial cell-cell communication not only disrupts this signaling process, but also contributes to pathologic disease progression. Expanding our understanding of those processes that mediate endothelial cell-cell communication is an important step in the approach to treatment of disease processes.

Indexed as

Cell CommunicationCell DifferentiationDisease ProgressionEndotheliumEndothelium, VascularHomeostasisHumansDevelopmentDiseaseDysfunctionEndotheliumHeterogeneitySignaling

Identifiers

PMID32172808
PMCPMC7078071
OpenAlexW3004283504

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.