ArticleCardiology in the young2020
Lean body mass is the strongest anthropometric predictor of left ventricular mass in the obese paediatric population.
Article in Cardiology in the young, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Quadratus Lumborum Block Reduced Postpartum Uterine Pain After Normal Spontaneous Delivery: A Prospective, Randomized, Double-Blind, Controlled Trial.Health science reports · 2026Article
- Sex- and body surface area-specific distribution and developmental trends of left ventricular structure and function during early adolescence.European journal of pediatrics · 2026Article
- Relationship of Left Ventricular Mass to Lean Body Mass in the Obese Pediatric Population.Pediatric cardiology · 2024Article
- Lean body mass positively associate with blood pressure in Chinese adults: the roles of ages and body fat distribution.BMC public health · 2023Article
- Defining left ventricular remodeling using lean body mass allometry: a UK Biobank study.European journal of applied physiology · 2023Article
- A prospective cohort study on the association of lean body mass estimated by mid-upper arm muscle circumference with hypertension risk in Chinese residents.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundIndexing left ventricular mass to body surface area or height2.7 leads to inaccuracies in diagnosing left ventricular hypertrophy in obese children. Lean body mass predictive equations provide the opportunity to determine the utility of lean body mass in indexing left ventricular mass. Our objectives were to compare the diagnostic accuracy of predicted lean body mass, body surface area, and height in detecting abnormal left ventricle mass in obese children.
methodsObese non-hypertensive patients aged 4-21 years were recruited prospectively. Dual-energy X-ray absorptiometry was used to measure lean body mass. Height, weight, sex, race, and body mass index z-score were used to calculate predicted lean body mass.
resultsWe enrolled 328 patients. Average age was 12.6 ± 3.8 years. Measured lean body mass had the strongest relationship with left ventricular mass (R2 = 0.84, p < 0.01) compared to predicted lean body mass (R2 = 0.82, p < 0.01), body surface area (R2 = 0.80, p < 0.01), and height2.7 (R2 = 0.65, p < 0.01). Of the clinically derived variables, predicted lean body mass was the only measure to have an independent association with left ventricular mass (β = 0.90, p < 0.01). Predicted lean body mass was the most accurate scaling variable in detecting left ventricular hypertrophy (positive predictive value = 88%, negative predictive value = 99%).
conclusionsLean body mass is the strongest predictor of left ventricular mass in obese children. Predicted lean body mass is the most accurate anthropometric scaling variable for left ventricular mass in left ventricular hypertrophy detection. Predicted lean body mass should be considered for clinical use as the body size correcting variable for left ventricular mass in obese children.
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