Evidence map›Paper›PMID 32172619›Full record

ArticleHypertension (Dallas, Tex. : 1979)2020

Regional Patterns and Association Between Obesity and Hypertension in Africa: Evidence From the H3Africa CHAIR Study.

Onoja M Akpa, Felix Made, Akinlolu Ojo, Bruce Ovbiagele, Dwomoa Adu, Ayesha A Motala, Bongani M Mayosi, Sally N Adebamowo, Mark E Engel, Bamidele Tayo and 30 more

Open access · hybridAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 8 pooled it
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 8 syntheses or guidelines pooled it, 85 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

40 authors at 20 institutions in 7 countries.

Onoja M AkpaFrom the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.
Felix MadeThe Epidemiology and Surveillance Section, National Institute for Occupational Health, National Health Laboratory Services, Gauteng Region, South Africa (F. Made).
Akinlolu OjoClinical research and global health initiatives, University of Arizona Health Sciences (A.O.).
Bruce OvbiageleDepartment of Neurology, University of California, San Francisco CA, USA (B.O.).
Dwomoa AduSchool of Medicine and Dentistry, University of Ghana, Accra, Ghana (D.A.).
Ayesha A MotalaDepartment of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa (A.A.M.).
Bongani M MayosiDepartment of Medicine, Groote Schuur Hospital (B.M.M.), University of Cape Town, South Africa.
Sally N AdebamowoDepartment of Epidemiology and Public Health, Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA (S.N.A.).
Mark E EngelDivision of Cardiology, Department of Medicine (M.E.E., C.C.), University of Cape Town, South Africa.
Bamidele TayoDepartment of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL (B.T.).
Charles RotimiCenter for Research on Genomics and Global Health, NHGRI, NIH, Bethesda, MD, USA (C.R.).
Babatunde SalakoFrom the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.
Rufus AkinyemiFrom the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.
Mulugeta GebregziabherDepartment of Public Health Sciences, Medical University of South Carolina, Charleston SC, USA (M.G.).
Fred SarfoKwame Nkrumah University of Science and Technology, Kumasi, Ghana (F.S.).
Kolawole WahabDepartment of Medicine, University of Ilorin, Nigeria (K. Wahab).
Godfred AgongoNavrongo Health Research Centre, Ghana (G. Agongo, E.A.N.).
Marianne AlbertsDepartment of Pathology and Medical Science, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa (M.A., F. Mashinya).
Stuart A AliSydney Brenner Institute for Molecular Bioscience and Division of Human Genetics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (O.M.A., F. Made, S.A.A., M.R.).
Gershim AsikiAfrican Population and Health Research Center, Nairobi, Kenya (G. Asiki, S.F.M.).
Romuald P BouaInstitut de Recherche en Sciences de la Sante, Clinical Research Unit of Nanoro, Burkina Faso (R.P.B., H.S.).
F Xavier Gómez-OlivéMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (F.X.G.-O., S.T.).
Felistas MashinyaDepartment of Pathology and Medical Science, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa (M.A., F. Mashinya).
Lisa MicklesfieldMRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (L.M., S.A.N.).
Shukri F MohamedAfrican Population and Health Research Center, Nairobi, Kenya (G. Asiki, S.F.M.).
Engelbert A NonterahNavrongo Health Research Centre, Ghana (G. Agongo, E.A.N.).
Shane A NorrisMRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (L.M., S.A.N.).
Hermann SorghoInstitut de Recherche en Sciences de la Sante, Clinical Research Unit of Nanoro, Burkina Faso (R.P.B., H.S.).
Stephen TollmanMRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (F.X.G.-O., S.T.).
Rulan S ParekhDepartments of Pediatrics, Medicine and Epidemiology, Hospital for Sick Children, University Health Network and University of Toronto, Canada (R.S.P.).
Chishala ChishalaDivision of Cardiology, Department of Medicine (M.E.E., C.C.), University of Cape Town, South Africa.
Kenneth EkoruCenter for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD (K.E.).
Salina P WaddyDepartment of Neurology, Atlanta Veterans Affairs Medical Center, Decatur, GA (S.P.W.).
Emmanuel PeprahCollege of Global Public Health, New York University, New York, NY (E.P.).
George A MensahCenter for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD (G.A.M.).
Ken WileyDivision of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD (K. Wiley).
Jennifer TroyerHuman Heredity and Health in Africa, Division of Genome Sciences (J.T.), National Institutes of Health, Bethesda, MD.
Michèle Ramsay *Sydney Brenner Institute for Molecular Bioscience and Division of Human Genetics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (O.M.A., F. Made, S.A.A., M.R.).
Mayowa O Owolabi *From the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.
as members of the CVD Working Group of the H3Africa Consortium
University of the Witwatersrand · ZANational Human Genome Research Institute · USUniversity of Ibadan · NGAfrican Population and Health Research Center · KEAgincourt Health and Socio-Demographic Surveillance System · ZAInstitut de Recherche en Sciences de la Santé · BFNavrongo Health Research Centre · GHUniversity of Cape Town · ZAUniversity of Limpopo · ZACommunity Initiatives · USGroote Schuur Hospital · ZAKwame Nkrumah University of Science and Technology · GHLoyola University Chicago · USMedical University of South Carolina · USNational Heart Lung and Blood Institute · USNational Institute for Occupational Health · ZANew York University · USU-M Rogel Cancer CenterUniversity Health Network · CAUniversity of California, San Francisco · US

Funding

Shared Core: Biobanking, Bioinformatics and Data ManagementU54HG006938 · NHGRI · WITS HEALTH CONSORTIUM (PTY), LTD · PI RAMSAY, MICHELE MICHELE · 2012 to 2022
$12.2M
H3Africa Kidney Disease Research NetworkU54HG006939 · NHGRI · NOGUCHI MEMORIAL INSTITUTE / MEDICAL RES · PI ADU, DWOMOA, OJO, AKINLOLU OLUSEUN · 2012 to 2017
$6.1M
African Collaborative Center for Microbiome and Genomics Research (ACCME)U54HG006947 · NHGRI · INSTITUTE OF HUMAN VIROLOGY · PI ADEBAMOWO, CLEMENT ADEBAYO · 2013 to 2018
$5.7M
Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
H3Africa Kidney Disease Research Network- Collaborative CentersU54DK116913 · NIDDK · COLLEGE OF HEALTH SCIENCES, UNIVERSITY OF GHANA · PI ADU, DWOMOA, OJO, AKINLOLU OLUSEUN · 2017 to 2021
$4.1M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
African Neurobiobank for Precision Stroke Medicine - (ELSI) ProjectU01HG010273 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI AKINYEMI, RUFUS OLUSOLA, ARULOGUN, OYEDUNNI SOLA · 2018 to 2022
$512k
NHGRI NIH HHS U01 HG010273NHGRI NIH HHS U54 HG006938NHGRI NIH HHS U54 HG006939NHGRI NIH HHS U54 HG006947NHGRI NIH HHS U54 HG007479NIDDK NIH HHS U54 DK116913NINDS NIH HHS R01 NS107900Wellcome Trust 099313/B/12/ZWellcome Trust 099313/Z/12/Z
6 · The paper itself

Abstract

Hypertension and obesity are the most important modifiable risk factors for cardiovascular diseases, but their association is not well characterized in Africa. We investigated regional patterns and association of obesity with hypertension among 30 044 continental Africans. We harmonized data on hypertension (defined as previous diagnosis/use of antihypertensive drugs or blood pressure [BP]≥140/90 mmHg/BP≥130/80 mmHg) and obesity from 30 044 individuals in the Cardiovascular H3Africa Innovation Resource across 13 African countries. We analyzed data from population-based controls and the Entire Harmonized Dataset. Age-adjusted and crude proportions of hypertension were compared regionally, across sex, and between hypertension definitions. Logit generalized estimating equation was used to determine the independent association of obesity with hypertension (

Indexed as

AdultAfricaAgedAntihypertensive AgentsBody Mass IndexCase-Control StudiesCross-Sectional StudiesFemaleHumansHypertensionMaleMiddle AgedObesityOverweightPrevalenceRisk FactorsAntihypertensive AgentsAfricablood pressurehypertensionobesityrisk factors

Identifiers

PMID32172619
PMCPMC7176339
OpenAlexW3011773069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.