Evidence map›Paper›PMID 32172512›Full record

ArticleFood and environmental virology2020

Detection and Characterization of Hepatitis E Virus Genotype 3 in Wastewater and Urban Surface Waters in Germany.

Sophia Beyer, Regine Szewzyk, Regina Gnirss, Reimar Johne, Hans-Christoph Selinka

Open access · hybridAbstract read
In one paragraph

Article in Food and environmental virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sophia BeyerSection II 1.4 Microbiological Risks, German Environment Agency (UBA), Corrensplatz 1, 14195, Berlin, Germany.
Regine SzewzykSection II 1.4 Microbiological Risks, German Environment Agency (UBA), Corrensplatz 1, 14195, Berlin, Germany.
Regina GnirssBerliner Wasserbetriebe (BWB), Cicerostr. 24, 10709, Berlin, Germany.
Reimar JohneGerman Federal Institute for Risk Assessment (BfR), Max-Dohrn-Straße 8-10, 10589, Berlin, Germany.
Hans-Christoph SelinkaSection II 1.4 Microbiological Risks, German Environment Agency (UBA), Corrensplatz 1, 14195, Berlin, Germany. hans-christoph.selinka@uba.de.
German Environment Agency · DEBerliner Wasserbetriebe (Germany) · DEFederal Institute for Risk Assessment · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In highly populated areas, environmental surveillance of wastewater and surface waters is a key factor to control the circulation of viruses and risks for public health. Hepatitis E virus (HEV) genotype 3 is considered as an emerging pathogen in industrialized countries. Therefore, this study was carried out to determine the prevalence of HEV in environmental waters in urban and suburban regions in Germany. HEV was monitored in water samples using quantitative RT-PCR (RT-qPCR) and nested RT-PCR without or with virus concentration via polyethylene glycol precipitation or ultracentrifugation. By RT-qPCR, 84-100% of influent samples of wastewater treatment plants were positive for HEV RNA. Genotypes HEV-3c and 3f were identified in wastewater, with HEV-3c being the most prevalent genotype. These data correlate with subtypes identified earlier in patients from the same area. Comparison of wastewater influent and effluent samples revealed a reduction of HEV RNA of about 1 log

Indexed as

Environmental MonitoringGenotypeGermanyHepatitis EHepatitis E virusHumansRiversRNA, ViralWastewaterRNA, ViralWastewaterCombined sewer overflowGenotypingHepatitis E virusMonitoringSurface waterWastewater

Identifiers

PMID32172512
PMCPMC7225198
OpenAlexW3010920683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.