Evidence map›Paper›PMID 32172458›Full record

ArticleCellular and molecular neurobiology2020

L-type Voltage-Gated Calcium Channel Modulators Inhibit Glutamate-Induced Morphology Changes in U118-MG Astrocytoma Cells.

Mitra Sadat Tabatabaee, Frederic Menard

Open access · greenAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mitra Sadat TabatabaeeDepartment of Biochemistry & Molecular Biology, I.K. Barber School of Sciences, University of British Columbia, Kelowna, BC, Canada.ORCID http://orcid.org/0000-0001-9412-1505
Frederic MenardDepartment of Biochemistry & Molecular Biology, I.K. Barber School of Sciences, University of British Columbia, Kelowna, BC, Canada. frederic.menard@ubc.ca.ORCID http://orcid.org/0000-0002-4135-4417
University of British Columbia · CA

Funding

Natural Sciences and Engineering Research Council of Canada (CA) RGPIN-2014-04982UBC Eminence Fund 62R10870
6 · The paper itself

Abstract

The excitatory neurotransmitter glutamate evokes physiological responses within the astrocytic network that lead to fine morphological changes. However, the mechanism by which astrocytes couple glutamate sensing with cellular calcium rise remains unclear. We tested a possible connection between L-type voltage-gated calcium channels (Ca

Indexed as

AstrocytesAstrocytomaCalciumCalcium Channels, L-TypeGlutamic AcidHumansProtein SubunitsSignal TransductionSynaptic TransmissionCalciumCalcium Channels, L-TypeGlutamic AcidProtein SubunitsAstrocytesFilopodiagenesisGlutamateVoltage-gated calcium channels

Identifiers

PMID32172458
PMCPMC11448807
OpenAlexW3011547656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.