Evidence map›Paper›PMID 32171786›Full record

ReviewAgeing research reviews2020

A multidimensional approach to frailty in older people.

Alberto Pilotto, Carlo Custodero, Stefania Maggi, Maria Cristina Polidori, Nicola Veronese, Luigi Ferrucci

Registry-linked trialOpen access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Ageing research reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07572851 (Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care), which is not on this map. Cited by 202 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
202citing papers in PubMed, 9 pooled it
21.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07572851 enrolling by invitationnot on this mapstarted 2026, after this paper: background citation

Observational Study of Functional Changes and Fall Risk in Older Adults Participating in a Multicomponent Frailty and Falls Prevention Program in Primary Care

TypeobservationalSponsorUniversity of VigoRan2026 to 2026Enrolled56ConditionsFrail Elderly, Fall RiskArmsMulticomponent Exercise Program- 1 times per week., Multicomponent Exercise Program- 2 times per week.
3 · Its place in the literature

Who cites it

202 citing papers in PubMed, 9 syntheses or guidelines pooled it, 375 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Article
  15. Article
  16. Observational
  17. Article
  18. Review
  19. Article
  20. Article

142 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Alberto PilottoDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy; Geriatrics Unit, Department of Geriatric Care, Orthogeriatrics and Rehabilitation, E.O. Ospedali Galliera, Genova, Italy. Electronic address: alberto.pilotto@galliera.it.
Carlo CustoderoDepartment of Interdisciplinary Medicine, University of Bari Aldo Moro, Bari, Italy.
Stefania MaggiNational Research Council (CNR), Aging Section, Padova, Italy.
Maria Cristina PolidoriAgeing Clinical Research, University Hospital of Cologne, Germany.
Nicola VeroneseGeriatrics Unit, Department of Geriatric Care, Orthogeriatrics and Rehabilitation, E.O. Ospedali Galliera, Genova, Italy; Azienda ULSS 3 Serenissima, Primary Care Department, District 3, Venice, Italy.
Luigi FerrucciNational Institute on Aging, NIH, Baltimore, MD, United States.
University of Bari Aldo Moro · ITAzienda ULSS 9 TREVISO · ITNational Institute on Aging · USNational Research Council · ITUniversity Hospital Cologne · DE

Funding

Intramural NIH HHS Z99 AG999999
6 · The paper itself

Abstract

Frailty is an important factor determining a higher risk of adverse health outcomes in older adults. Although scientific community in the last two decades put a lot of effort for its definition, to date no consensus was reached on its assessment. The mainstream thinking describes frailty as a loss of physical functions or as accumulation of multiple deficits. Recently, a novel conceptual model of frailty has emerged based on the loss of harmonic interaction between multiple domains (also referred as dimensions) including genetic, biological, functional, cognitive, psychological and socio-economic domain that ultimately lead to homeostatic instability. Therefore, the multidimensional aspects of frailty condition could be captured by the comprehensive geriatric assessment (CGA) and its derived Multidimensional Prognostic Index (MPI). This instrument has been applied in different clinical settings and in several cohorts of older adults with specific acute and chronic diseases, showing always excellent accuracy in stratifying population according the mortality risk and other negative health outcomes, i.e. hospitalization, institutionalization or admission to homecare services. This MPI "plasticity" provides a single numerical prognostic index which could be helpful in clinical decision making for the management of frail older adults.

Indexed as

Frail ElderlyFrailtyGeriatric AssessmentAgedAged, 80 and overHumansPrognosisComprehensive geriatric assessmentFrailtyMultidimensional prognostic index

Identifiers

PMID32171786
PMCPMC7461697
OpenAlexW3012418802

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.