ArticleJournal of cardiothoracic surgery2020
The elevated admission white blood cell count relates to adverse surgical outcome of acute Stanford type a aortic dissection.
Article in Journal of cardiothoracic surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Prognostic role of neutrophil-to-lymphocyte ratio in aortic disease: a meta-analysis of observational studies.Journal of cardiothoracic surgery · 2020Pooled it
- Development and validation of a risk prediction model for postoperative pneumonia in adult patients undergoing Stanford type A acute aortic dissection surgery: a case control study.Journal of cardiothoracic surgery · 2022Trial
- CHA2DS2-VA Score Can Be Used to Predict In-Hospital Mortality in Patients with Acute Aortic Dissection.Brazilian journal of cardiovascular surgery · 2026Article
- Development and validation of a nomogram-based risk prediction model for postoperative delirium in patients with stanford type A aortic dissection.Journal of cardiothoracic surgery · 2026Observational
- Clinical presentation, aetiological characteristics, risk factors and in-hospital outcome of nosocomial infection following acute aortic dissection surgery in adult patients.BMC cardiovascular disorders · 2025Article
- Systematic Review and Meta-analysis of Admission Inflammatory Biomarkers for Evaluating Prognosis in Acute Type A Aortic Dissection.Aorta (Stamford, Conn.) · 2025Article
- Predictive Value of the White Blood Cells Count for the Prognosis of Hospitalized Patients with Acute Aortic Dissection.Reviews in cardiovascular medicine · 2025Article
- Predicting Mortality Following Odontoid Fracture Fixation in Elderly Patients: CAADS-16 Score.Global spine journal · 2025Article
- Platelet-to-white blood cell ratio as a predictor of postoperative outcomes in acute type A aortic dissection: a single-center retrospective analysis.Frontiers in cardiovascular medicine · 2025Article
- Prognostic Value of Biomarkers in Acute Aortic Dissection: Analysis of Clinical Outcomes and Mortality.Emergency medicine international · 2025Article
- Inflammatory Trajectory and Anti-Inflammatory Pharmacotherapy in Frozen Elephant Trunk-Treated Acute Type I Aortic Dissection.Journal of the Society for Cardiovascular Angiography & Interventions · 2024Article
- Eosinophil Recovery Time Is Associated with Clinical Outcomes in Patients with Type A Acute Aortic Dissection: a Retrospective Cohort Study.Journal of cardiovascular translational research · 2024Article
- Short- and Long-term survival prediction in patients with acute type A aortic dissection undergoing open surgery.Journal of cardiothoracic surgery · 2024Article
- Postoperative hyper-inflammation as a predictor of poor outcomes in patients with acute type A aortic dissection (ATAAD) undergoing surgical repair.Journal of cardiothoracic surgery · 2024Article
- A predictive model for postoperative adverse outcomes following surgical treatment of acute type A aortic dissection based on machine learning.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Prediction of in-hospital death following acute type A aortic dissection.Frontiers in public health · 2023Article
- Prognostic significance of neutrophil count on in-hospital mortality in patients with acute type A aortic dissection.Frontiers in cardiovascular medicine · 2023Article
- Prognostic Impact of Systemic Coagulation-Inflammation Index in Acute Type A Aortic Dissection Surgery.JACC. Asia · 2022Article
- Intestinal barrier dysfunction is involved in the development of systemic inflammatory responses and lung injury in type A aortic dissection: a case-control study.Journal of thoracic disease · 2022Article
- Impacts of eosinophil percentage on prognosis acute type A aortic dissection patients.BMC cardiovascular disorders · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of the study was to examine the association between white blood cell count (WBCc) on admission and early outcome in patients with the acute Stanford type A aortic dissection (TAAD).
methodsFrom January 2012 to December 2018, we retrospectively evaluated a series of 331 consecutive patients underwent surgery for TAAD in Tongji Hospital. The patients were divided into 2 groups based on the WBCc, i.e. the normal WBCc group (WBCc≤11 × 10
resultsThe in-hospital mortality was nearly 3 time higher in the leukocytosis group than in the normal WBCc group (20.9% vs.8.1%, P = 0.001), and 15.1% overall. For the circulatory arrest, there was significant higher mortality in patients with leukocytosis than normal WBCc group (26.1%vs.8.9%, P = 0.001). After adjustment for confounding factors, the leukocytosis was found to be a strong independent predictor of in-hospital mortality (odds ratio = 3.10; 95% confidence interval 1.38 to 6.97, P = 0.006). The leukocytosis was also a risk factor of adverse events (odds ratio = 1.80; 95% confidence interval 1.07 to 3.04, P = 0.027).
conclusionsThe WBCc within 24 h of admission for TAAD is a strong and independent predictor of in-hospital mortality as well as short-term clinical events. The results of this study have important clinical implications for risk-stratifying patients with TAAD.
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