Evidence map›Paper›PMID 32171292›Full record

ArticleBMC oral health2020

A pilot study: a possible implication of Candida as an etiologically endogenous pathogen for oral lichen planus.

Hong He, Xinyu Xia, Haiping Yang, Qiao Peng, Jiaoer Zheng

Abstract read
In one paragraph

Article in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical and mycological analysis of colonization by Candida spp. in oral leukoplakia and oral lichen planus.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Evaluation of the Distribution ofBioMed research international · 2022
    Article
  10. The Implication ofMaedica · 2021
    Article
  11. Article
  12. Oral lichen planus: a microbiologist point of view.International microbiology : the official journal of the Spanish Society for Microbiology · 2021
    Review
  13. Oral lichen planus induced by long-term use of antimicrobials for recurrent aphthous ulcer: A case report and literature review.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2021
    Review
  14. International journal of health sciences
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hong HeThe Affiliated Stomatology Hospital, Zhejiang University School of Medicine, Yan'an Road, Hangzhou, 310006, China. honghehh@zju.edu.cn.ORCID 0000-0003-1299-0868
Xinyu XiaThe Affiliated Stomatology Hospital, Zhejiang University School of Medicine, Yan'an Road, Hangzhou, 310006, China.
Haiping YangThe Affiliated Stomatology Hospital, Zhejiang University School of Medicine, Yan'an Road, Hangzhou, 310006, China.
Qiao PengSchool of Medicine, Zhejiang University, Hangzhou, China.
Jiaoer ZhengThe Affiliated Stomatology Hospital, Zhejiang University School of Medicine, Yan'an Road, Hangzhou, 310006, China. rainbow050607@126.com.

Funding

Baoshi Oversea Scholarship 2013-2015 zups1507China Scholarship Council [2009]3004National and provincial Health Commission Co-construction Fund WKJ-ZJ-1623National Health Commission Public Welfare Fund 201502018National Key R&D Program of China 2016YFC0902702Research Program from Zhejiang Hygiene Bureau 2013KYB247Science and technology Office of Zhejiang Province 2008C33026 [2011]666Scientific Research Foundation for the Returned Oversea Chinese Scholar from HR Office of Zhejiang Province J20120036Zhejiang Province Public Welfare Technology Application Research Project yxyb20172030
6 · The paper itself

Abstract

backgroundThe aim of this study was to investigate the prevalence and genotypic profiles of Candida albicans in patients with oral lichen planus (OLP). MATERIALS AND

methodsPositive rates and genotypic profiles of Candida albicans strains from OLP patients and healthy controls were analyzed. Random amplified polymorphic DNA and internal transcribed spacer of ribosome DNA polymerase chain reactions were used to sequence the DNA of these strains, and then their genetic similarity was measured using BLAST, UIV Band, and Vector NTI Suite Sequence Analyses Software.

resultsThe prevalence of C. albicans strains detected from erosive-OLP, non-erosive OLP, and normal individuals was 18.87, 18.75, and 7.92%, respectively. Four different genotypes were revealed by the two methods. To be specific, type I was found only in the healthy subjects; type II a and II b were found in non-erosive OLP, and type III was identified in erosive OLP. Intragroup similarity coefficients, i.e. S

conclusionsThe genotypic results of C. albicans in OLP revealed an endogenous rather than exogenous infection of C. albicans. In addition, a possible pathogenic role of C. albicans in OLP, with the etiologic sense contributing to a more proper recognition on the pathogenesis, development, and progression of OLP, as well as some strategies for its diagnosis and treatment were identified.

Indexed as

AdultAgedCandida albicansCandidiasis, OralCase-Control StudiesFemaleGenotypeHumansLichen Planus, OralMaleMiddle AgedPolymerase Chain ReactionRandom Amplified Polymorphic DNA TechniqueSequence Analysis, DNACandida albicansEndogenous infectionEtiologyHomology similarity coefficient SABITS sequenceOral lichen planus

Identifiers

PMID32171292
PMCPMC7071738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.