Evidence map›Paper›PMID 32171101›Full record

ArticleBiomaterials2020

Radio-metal cross-linking of alginate hydrogels for non-invasive in vivo imaging.

P Stephen Patrick, Joseph C Bear, Heather E Fitzke, May Zaw-Thin, Ivan P Parkin, Mark F Lythgoe, Tammy L Kalber, Daniel J Stuckey

Abstract read
In one paragraph

Article in Biomaterials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. X-Ray Visible Protein Scaffolds by Bulk Iodination.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Detecting and Monitoring Hydrogels with Medical Imaging.ACS biomaterials science & engineering · 2021
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

P Stephen PatrickCentre for Advanced Biomedical Imaging, Division of Medicine, University College London, London, WC1E 6DD, UK. Electronic address: peter.patrick@ucl.ac.uk.
Joseph C BearSchool of Life Science, Pharmacy & Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, KT1 2EE, UK.
Heather E FitzkeCentre for Advanced Biomedical Imaging, Division of Medicine, University College London, London, WC1E 6DD, UK.
May Zaw-ThinCentre for Advanced Biomedical Imaging, Division of Medicine, University College London, London, WC1E 6DD, UK.
Ivan P ParkinMaterials Chemistry Centre, Department of Chemistry, University College London, 20 Gordon Street, London, WC1H 0AJ, UK.
Mark F LythgoeCentre for Advanced Biomedical Imaging, Division of Medicine, University College London, London, WC1E 6DD, UK.
Tammy L KalberCentre for Advanced Biomedical Imaging, Division of Medicine, University College London, London, WC1E 6DD, UK.
Daniel J StuckeyCentre for Advanced Biomedical Imaging, Division of Medicine, University College London, London, WC1E 6DD, UK. Electronic address: d.stuckey@ucl.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/M009513/1British Heart Foundation FS/15/33/31608British Heart Foundation RM/17/1/33377Medical Research Council MR/J013110/1Medical Research Council MR/K026739/1Medical Research Council MR/R026416/1Wellcome TrustWellcome Trust 212937/Z/18/Z
6 · The paper itself

Abstract

Alginate hydrogels are cross-linked polymers with high water content, tuneable chemical and material properties, and a range of biomedical applications including drug delivery, tissue engineering, and cell therapy. However, their similarity to soft tissue often renders them undetectable within the body using conventional bio-medical imaging techniques. This leaves much unknown about their behaviour in vivo, posing a challenge to therapy development and validation. To address this, we report a novel, fast, and simple method of incorporating the nuclear imaging radio-metal

Indexed as

AlginatesHydrogelsCross-Linking ReagentsGlucuronic AcidHexuronic AcidsIonsPolymersTissue EngineeringAlginatesCross-Linking ReagentsGlucuronic AcidHexuronic AcidsHydrogelsIonsPolymersBiological sciencesBiomaterialsDrug deliveryHydrogelsMedical sciencesSPECTStem cellsTissue engineering

Identifiers

PMID32171101
PMCPMC7103761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.